The continued threat of emerging flaviviruses
TC Pierson, MS Diamond - Nature microbiology, 2020 - nature.com
Flaviviruses are vector-borne RNA viruses that can emerge unexpectedly in human
populations and cause a spectrum of potentially severe diseases including hepatitis …
populations and cause a spectrum of potentially severe diseases including hepatitis …
Approved antiviral drugs over the past 50 years
E De Clercq, G Li - Clinical microbiology reviews, 2016 - Am Soc Microbiol
Since the first antiviral drug, idoxuridine, was approved in 1963, 90 antiviral drugs
categorized into 13 functional groups have been formally approved for the treatment of the …
categorized into 13 functional groups have been formally approved for the treatment of the …
Zika virus infects human cortical neural progenitors and attenuates their growth
The suspected link between infection by Zika virus (ZIKV), a re-emerging flavivirus, and
microcephaly is an urgent global health concern. The direct target cells of ZIKV in the …
microcephaly is an urgent global health concern. The direct target cells of ZIKV in the …
Zika virus: new clinical syndromes and its emergence in the western hemisphere
HM Lazear, MS Diamond - Journal of virology, 2016 - Am Soc Microbiol
Zika virus (ZIKV) had remained a relatively obscure flavivirus until a recent series of
outbreaks accompanied by unexpectedly severe clinical complications brought this virus …
outbreaks accompanied by unexpectedly severe clinical complications brought this virus …
Zika virus infects human placental macrophages
KM Quicke, JR Bowen, EL Johnson, CE McDonald… - Cell host & …, 2016 - cell.com
The recent Zika virus (ZIKV) outbreak in Brazil has been directly linked to increased cases of
microcephaly in newborns. Current evidence indicates that ZIKV is transmitted vertically from …
microcephaly in newborns. Current evidence indicates that ZIKV is transmitted vertically from …
Medicinal chemistry strategies for discovering antivirals effective against drug-resistant viruses
Y Ma, E Frutos-Beltrán, D Kang… - Chemical Society …, 2021 - pubs.rsc.org
During the last forty years we have witnessed impressive advances in the field of antiviral
drug discovery culminating with the introduction of therapies able to stop human …
drug discovery culminating with the introduction of therapies able to stop human …
Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis in∼ 40% of patients
A Gervais, F Rovida, MA Avanzini, S Croce… - Journal of Experimental …, 2023 - rupress.org
Mosquito-borne West Nile virus (WNV) infection is benign in most individuals but can cause
encephalitis in< 1% of infected individuals. We show that∼ 35% of patients hospitalized for …
encephalitis in< 1% of infected individuals. We show that∼ 35% of patients hospitalized for …
West Nile virus: an update on pathobiology, epidemiology, diagnostics, control and “one health” implications
West Nile virus (WNV) is an important zoonotic flavivirus responsible for mild fever to severe,
lethal neuroinvasive disease in humans, horses, birds, and other wildlife species. Since its …
lethal neuroinvasive disease in humans, horses, birds, and other wildlife species. Since its …
Modified vaccinia virus Ankara: history, value in basic research, and current perspectives for vaccine development
A Volz, G Sutter - Advances in virus research, 2017 - Elsevier
Abstract Safety tested Modified Vaccinia virus Ankara (MVA) is licensed as third-generation
vaccine against smallpox and serves as a potent vector system for development of new …
vaccine against smallpox and serves as a potent vector system for development of new …
[BOOK][B] Practical handbook of microbiology
LH Green, E Goldman - 2021 - books.google.com
Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …
knowledge and practical information about working with microorganisms. Useful to anyone …