Impact of obesity in critical illness

MR Anderson, MGS Shashaty - Chest, 2021 - Elsevier
The prevalence of obesity is rising worldwide. Adipose tissue exerts anatomic and
physiological effects with significant implications for critical illness. Changes in respiratory …

Lung Transplantation

JD Christie, D Van Raemdonck… - New England Journal of …, 2024 - Mass Medical Soc
Key Points Lung Transplantation Lung transplantation is growing worldwide as a recognized
treatment method for advanced lung diseases. Candidate selection for lung transplantation …

Obesity-related IL-18 impairs T-regulatory cell function and promotes lung ischemia–reperfusion injury

T Akimova, T Zhang, LM Christensen… - American Journal of …, 2021 - atsjournals.org
Rationale: Primary graft dysfunction (PGD) is a severe form of acute lung injury, leading to
increased early morbidity and mortality after lung transplant. Obesity is a major health …

Development of the lung transplant frailty scale (LT-FS)

JP Singer, JD Christie, JM Diamond… - The Journal of Heart and …, 2023 - Elsevier
Background Existing measures of frailty developed in community dwelling older adults may
misclassify frailty in lung transplant candidates. We aimed to develop a novel frailty scale for …

Clinical outcomes associated with computed tomography‐based body composition measures in lung transplantation: a systematic review

D Rozenberg, CE Orsso, K Chohan… - Transplant …, 2020 - Wiley Online Library
Computed tomography (CT) is gaining increased recognition in the assessment of body
composition in lung transplant (LTx) candidates as a prognostic marker of post‐transplant …

Body mass index and cause-specific mortality after lung transplantation in the United States

MR Anderson, E Cantu, M Shashaty… - Annals of the …, 2023 - atsjournals.org
Rationale: Low and high body mass index (BMI) are associated with increased mortality
after lung transplantation. Why extremes of BMI might increase risk of death is unknown …

ABCNet: A new efficient 3D dense‐structure network for segmentation and analysis of body tissue composition on body‐torso‐wide CT images

T Liu, J Pan, DA Torigian, P Xu, Q Miao… - Medical …, 2020 - Wiley Online Library
Purpose Quantification of body tissue composition is important for research and clinical
purposes, given the association between the presence and severity of several disease …

Adiposity and interstitial lung abnormalities in community-dwelling adults: The MESA cohort study

MR Anderson, JS Kim, M Allison, JT Giles, EA Hoffman… - Chest, 2021 - Elsevier
Background Obesity is associated with restrictive ventilatory defects and a faster rate of
decline in FVC. This association is not exclusively mediated by mechanical factors and may …

[HTML][HTML] Erector spinae muscle radiographic density is associated with survival after lung transplantation

Y Oshima, S Sato, TF Chen-Yoshikawa… - The Journal of Thoracic …, 2022 - Elsevier
Objective The study objective was to verify whether low preoperative radiographic density of
erector spinae muscles is associated with poor prognosis after lung transplantation …

Adipose Tissue Segmentation after Lung Slice Localization in Chest CT Images Based on ConvBiGRU and Multi-Module UNet

P Lei, J Li, J Yi, W Chen - Biomedicines, 2024 - mdpi.com
The distribution of adipose tissue in the lungs is intricately linked to a variety of lung
diseases, including asthma, chronic obstructive pulmonary disease (COPD), and lung …