Impact of COVID-19 on cardiovascular disease

I Vosko, A Zirlik, H Bugger - Viruses, 2023‏ - mdpi.com
Coronavirus disease 2019 (COVID-19) is a viral infection with the novel severe acute
respiratory distress syndrome corona virus 2 (SARS-CoV-2). Until now, more than 670 …

Potential cardiotoxic effects of remdesivir on cardiovascular system: a literature review

M Nabati, H Parsaee - Cardiovascular toxicology, 2022‏ - Springer
Abstract Corona disease 2019 (COVID-19) pandemic continues to spread around the world
with no efficacious treatment. Intravenous remdesivir is the only authorized drug for …

SARS-CoV-2 infection of human iPSC–derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19

JA Perez-Bermejo, S Kang, SJ Rockwood… - Science translational …, 2021‏ - science.org
Although coronavirus disease 2019 (COVID-19) causes cardiac dysfunction in up to 25% of
patients, its pathogenesis remains unclear. Exposure of human induced pluripotent stem cell …

Discovery and mechanism of SARS-CoV-2 main protease inhibitors

S Huff, IR Kummetha, SK Tiwari… - Journal of medicinal …, 2021‏ - ACS Publications
The emergence of a new coronavirus, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), presents an urgent public health crisis. Without available targeted therapies …

A comprehensive review on pharmacologic agents, immunotherapies and supportive therapeutics for COVID-19

K Sharun, R Tiwari, MI Yatoo, S Natesan… - Narra J, 2022‏ - pmc.ncbi.nlm.nih.gov
The emergence of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has affected many countries throughout …

Long COVID-19 and the heart: is cardiac mitochondria the missing link?

X Chang, NI Ismail, A Rahman, D Xu… - Antioxidants & redox …, 2023‏ - liebertpub.com
Significance: Although corona virus disease 2019 (COVID-19) has now gradually been
categorized as an endemic, the long-term effect of COVID-19 in causing multiorgan …

A sustainable approach for the removal methods and analytical determination methods of antiviral drugs from water/wastewater: A review

B Eryildiz, BY Gul, I Koyuncu - Journal of Water Process Engineering, 2022‏ - Elsevier
In the last years, antiviral drugs especially used for the treatment of COVID-19 have been
considered emerging contaminants because of their continuous occurrence and persistence …

Cardiovascular events and safety outcomes associated with remdesivir using a World Health Organization international pharmacovigilance database

SY Jung, MS Kim, H Li, KH Lee… - Clinical and …, 2022‏ - Wiley Online Library
Abstract On October 2020, the US Food and Drug Administration (FDA) approved remdesivir
as the first drug for the treatment of coronavirus disease 2019 (COVID‐19), increasing …

Drug repositioning in the COVID-19 pandemic: fundamentals, synthetic routes, and overview of clinical studies

ES Vaz, SV Vassiliades, J Giarolla, MC Polli… - European Journal of …, 2023‏ - Springer
Introduction Drug repositioning is a strategy to identify a new therapeutic indication for
molecules that have been approved for other conditions, aiming to speed up the traditional …

Remdesivir induces persistent mitochondrial and structural damage in human induced pluripotent stem cell-derived cardiomyocytes

M Kwok, C Lee, HS Li, R Deng, C Tsoi… - Cardiovascular …, 2022‏ - academic.oup.com
Aims Remdesivir is a prodrug of an adenosine triphosphate analogue and is currently the
only drug formally approved for the treatment of hospitalized coronavirus disease of 2019 …