The advent of Camptothecin added a new dimension in the field anticancer drug
development containing quinoline motif. Quinoline scaffold plays an important role in …

Quinolines have become important compounds because of their variety of applications in
medicinal, synthetic organic chemistry as well as in the field of industrial chemistry. In recent …

Late-stage modification of drug molecules is a fast method to introduce diversity into the
already biologically active scaffold. A notable number of analogs of mefloquine, chloroquine …

The resistance of pathogenic microbes to currently available antimicrobial agents has been
considered a global alarming concern. Hence, close attention should be paid to the …

The gallic acid (GA) obtained from the ethanolic extract of Pomegranate (Punica granatum)
pericarp, was successfully applied as a green and effective natural catalyst for the synthesis …

Based on the biologically active heterocycle quinoline, a series (18a-p) of quinoline
hydrazone analogues were prepared, starting from 6-bromo/6-chloro-2-methyl-quinolin-4-yl …

Quinoline is one of the most widely investigated scaffolds by synthetic chemists because of
its medicinal importance. A wide range of metal-catalyzed, metal-free, multi-step or domino …

Antibiotics are becoming gradually ineffective due to drug resistance, leading to greater
difficulty in the treatment of infectious diseases. Therefore, the development of new chemical …

Inspired by the role of organotin (IV) compounds as potential pharmaceutical agents, we
have synthesized a series of new diorganotin (IV) complexes (5–20) of hydrazone ligands (1 …

Quinolines are a prominent heterocyclic motif and crucial building blocks in creating
physiologically active compounds. Due to the fast development of novel medicines with a …