Chronic hepatitis B virus infection

WK Seto, YR Lo, JM Pawlotsky, MF Yuen - The Lancet, 2018 - thelancet.com
Chronic hepatitis B virus infection is a global public health threat that causes considerable
liver-related morbidity and mortality. It is acquired at birth or later via person-to-person …

Acute-on-chronic liver failure in cirrhosis

V Arroyo, R Moreau, PS Kamath, R Jalan… - Nature reviews Disease …, 2016 - nature.com
The definition of acute-on-chronic liver failure (ACLF) remains contested. In Europe and
North America, the term is generally applied according to the European Association for the …

Development of diagnostic criteria and a prognostic score for hepatitis B virus-related acute-on-chronic liver failure

T Wu, J Li, L Shao, J **n, L Jiang, Q Zhou, D Shi… - Gut, 2018 - gut.bmj.com
Objective The definition of acute-on-chronic liver failure (ACLF) based on cirrhosis,
irrespective of aetiology, remains controversial. This study aimed to clarify the …

[HTML][HTML] Acute-on-chronic liver failure: Definitions, pathophysiology and principles of treatment

G Zaccherini, E Weiss, R Moreau - JHEP reports, 2021 - Elsevier
The term acute-on-chronic liver failure (ACLF) defines an abrupt and life-threatening
worsening of clinical conditions in patients with cirrhosis or chronic liver disease. In recent …

Acute-on-chronic liver failure: terminology, mechanisms and management

SK Sarin, A Choudhury - Nature reviews Gastroenterology & hepatology, 2016 - nature.com
Acute-on-chronic liver failure (ACLF) is a distinct clinical entity and differs from acute liver
failure and decompensated cirrhosis in timing, presence of acute precipitant, course of …

Acute-on-chronic liver failure

W Bernal, R Jalan, A Quaglia, K Simpson, J Wendon… - The Lancet, 2015 - thelancet.com
Acute-on-chronic liver failure combines an acute deterioration in liver function in an
individual with pre-existing chronic liver disease and hepatic and extrahepatic organ …

Characteristics, diagnosis and prognosis of acute-on-chronic liver failure in cirrhosis associated to hepatitis B.

H Li, LY Chen, N Zhang, ST Li, B Zeng, M Pavesi… - Scientific reports, 2016 - nature.com
The diagnostic and prognostic criteria of acute-on-chronic liver failure (ACLF) were
developed in patients with no Hepatitis B virus (HBV) cirrhosis (CANONIC study). The aims …

Human umbilical cord-derived mesenchymal stem cells improve the function of liver in rats with acute-on-chronic liver failure via downregulating Notch and Stat1/Stat3 …

Y He, X Guo, T Lan, J **a, J Wang, B Li, C Peng… - Stem Cell Research & …, 2021 - Springer
Background Effective treatments for acute-on-chronic liver failure (ACLF) are lacking.
Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) have been applied in …

Acute-on-chronic liver failure in chronic hepatitis B: an update

RH Zhao, Y Shi, H Zhao, W Wu… - Expert review of …, 2018 - Taylor & Francis
Introduction Acute-on-chronic liver failure is a common pattern of end-stage liver disease in
clinical practice and occurs frequently in patients with chronic hepatitis B or HBV-related …

Acute-on-chronic liver failure: pathophysiological mechanisms and management

A Khanam, S Kottilil - Frontiers in medicine, 2021 - frontiersin.org
Acute-on-chronic liver failure (ACLF) is a multifaceted condition with poor treatment options
and high short-term mortality. ACLF can develop in patients with or without liver cirrhosis …