Background Animal studies show that peripheral inflammatory stimuli may activate
microglial cells in the brain implicating an important role for microglia in sepsis-associated …

Microglia, the resident immune cells of the central nervous system (CNS), play an important
role in CNS homeostasis during development, adulthood and ageing. Their phenotype and …

The hematopoietic system seeds the CNS with microglial progenitor cells during the fetal
period, but the subsequent cell generation dynamics and maintenance of this population …

Microglia constitute a highly specialized network of tissue-resident immune cells that is
important for the control of tissue homeostasis and the resolution of diseases of the CNS …

Insulin resistance is necessary but not sufficient for the development of type 2 diabetes.
Diabetes results when pancreatic beta-cells fail to compensate for insulin resistance by …

Numerous studies have reported the importance of microglial activation in various
pathological conditions, whereas little attention has been given to the point for dynamics of …

The blood–brain barrier (BBB) generally consists of endothelial tight junction barriers that
prevent the free entry of blood-derived substances, thereby maintaining the extracellular …

Inhibiting microglia proliferation after spinal cord injury improves recovery in mice and
nonhuman primates - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Microglia, macrophages of the central nervous system, play an important role in brain
homeostasis. Their origin has been unclear. Recent fate‐map** experiments have …

Neuroinflammation is a pathological mechanism contributing to neurodegenerative
diseases. For in-depth studies of neuroinflammation, several animal models reported …