Calcific aortic valve disease: from molecular and cellular mechanisms to medical therapy

S Kraler, MC Blaser, E Aikawa, GG Camici… - European heart …, 2022 - academic.oup.com
Calcific aortic valve disease (CAVD) is a highly prevalent condition that comprises a disease
continuum, ranging from microscopic changes to profound fibro-calcific leaflet remodelling …

Materials-based nanotherapeutics for injured and diseased bone

CS Lee, RK Singh, HS Hwang, NH Lee… - Progress in Materials …, 2023 - Elsevier
Severe injuries and diseases of bone tissue caused by congenital disorder, extrinsic trauma,
infection, and osteosarcoma resection face significant challenges for complete recovery. The …

Osteoblast-derived VEGF regulates osteoblast differentiation and bone formation during bone repair

K Hu, BR Olsen - The Journal of clinical investigation, 2016 - Am Soc Clin Investig
Osteoblast-derived VEGF is important for bone development and postnatal bone
homeostasis. Previous studies have demonstrated that VEGF affects bone repair and …

Self-healing DNA-based injectable hydrogels with reversible covalent linkages for controlled drug delivery

S Basu, S Pacelli, A Paul - Acta Biomaterialia, 2020 - Elsevier
Injectable hydrogels represent a valuable tool for the delivery of therapeutic molecules
aimed to restore the functionality of damaged tissues. In this study, we report the design of a …

An improved osseointegration of metal implants by pitavastatin loaded multilayer films with osteogenic and angiogenic properties

W Chen, G **e, Y Lu, J Wang, B Feng, Q Wang, K Xu… - Biomaterials, 2022 - Elsevier
An increasing number of works have highlighted the importance of metal implants surface
modification in enhancing bone defect healing through the synergistic osteogenesis …

Surface-modified titanium and titanium-based alloys for improved osteogenesis: A critical review

J Li, Y Zheng, Z Yu, RK Kankala, Q Lin, J Shi, C Chen… - Heliyon, 2024 - cell.com
As implantable materials, titanium, and its alloys have garnered enormous interest from
researchers for dental and orthopedic procedures. Despite their success in wide clinical …

Rational design of bioactive hydrogels toward periodontal delivery: from pathophysiology to therapeutic applications

Y Yin, S Yang, D Ai, H Qin, Y Sun, X **a… - Advanced Functional …, 2023 - Wiley Online Library
Periodontitis is a biofilm‐induced, host‐mediated inflammatory disease that results in
periodontal tissue destruction. The design of functional biomaterials based on disease …

A ROS-responsive simvastatin nano-prodrug and its fibronectin-targeted co-delivery system for atherosclerosis treatment

R Zhao, X Ning, M Wang, H Wang, G **ng… - … Applied Materials & …, 2022 - ACS Publications
Nanoprodrugs with responsive release properties integrate the advantages of stimuli-
responsive prodrugs and nanotechnology. They would provide ultimate opportunity in …

The effects of statins on dental and oral health: a review of preclinical and clinical studies

S Tahamtan, F Shirban, M Bagherniya… - Journal of translational …, 2020 - Springer
The statin family of drugs are safe and effective therapeutic agents for the treatment of
arteriosclerotic cardiovascular disease (CVD). Due to a wide range of health benefits in …

[HTML][HTML] Decellularized and biological scaffolds in dental and craniofacial tissue engineering: A comprehensive overview

M Yazdanian, AH Arefi, M Alam, K Abbasi… - journal of materials …, 2021 - Elsevier
Dental problems including cavities, periodontitis, apical periodontitis, and pulpitis are among
the most cost-consuming burden for both patients and the health care system all over the …