Neurons have diverse molecular, morphological, connectional and functional properties. We
believe that the only realistic way to manage this complexity—and thereby pave the way for …

Oligodendrocyte precursor cells (OPCs) originate in the ventricular zones (VZs) of the brain
and spinal cord and migrate throughout the develo** central nervous system (CNS) …

Patterns of gene expression can be used to characterize and classify neuronal types. It is
challenging, however, to generate taxonomies that fulfill the essential criteria of being …

Classification and characterization of neuronal types are critical for understanding their
function and dysfunction. Neuronal classification schemes typically rely on measurements of …

In the retina, photoreceptors pass visual information to interneurons, which process it and
pass it to retinal ganglion cells (RGCs). Axons of RGCs then travel through the optic nerve …

The development of single-cell RNA sequencing (scRNA-seq) has allowed high-resolution
analysis of cell-type diversity and transcriptional networks controlling cell-fate specification …

Abstract Structure and function are highly correlated in the vertebrate retina, a sensory tissue
that is organized into cell layers with microcircuits working in parallel and together to encode …

The adult CNS contains an abundant population of oligodendrocyte precursor cells (NG2+
cells) that generate oligodendrocytes and repair myelin, but how these ubiquitous …

The visual signal processing in the retina requires the precise organization of diverse
neuronal types working in concert. While single-cell omics studies have identified more than …

The molecular diversification of cell surface molecules has long been postulated to impart
specific surface identities on neuronal cell types. The existence of unique cell surface …