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Plasmodium vivax: the potential obstacles it presents to malaria elimination and eradication
Initiatives to eradicate malaria have a good impact on P. falciparum malaria worldwide. P.
vivax, however, still presents significant difficulties. This is due to its unique biological traits …
vivax, however, still presents significant difficulties. This is due to its unique biological traits …
Recent advances, challenges and updates on the development of therapeutics for malaria
Malaria has developed as a serious worldwide health issue as a result of the introduction of
resistant Plasmodium species strains. Because of the common chemo resistance to most of …
resistant Plasmodium species strains. Because of the common chemo resistance to most of …
A Pvs25 mRNA vaccine induces complete and durable transmission-blocking immunity to Plasmodium vivax
Plasmodium vivax (P. vivax) is the major malaria parasite outside of Africa and no vaccine is
available against it. A vaccine that interrupts parasite transmission (transmission-blocking …
available against it. A vaccine that interrupts parasite transmission (transmission-blocking …
Transmission-reducing and -enhancing monoclonal antibodies against Plasmodium vivax gamete surface protein Pvs48/45
Gamete surface protein P48/45 has been shown to be important for male gamete fertility and
a strong candidate for the development of a malaria transmission-blocking vaccine (TBV) …
a strong candidate for the development of a malaria transmission-blocking vaccine (TBV) …
The parasite intraerythrocytic cycle and human circadian cycle are coupled during malaria infection
During infections with the malaria parasites Plasmodium vivax, patients exhibit rhythmic
fevers every 48 h. These fever cycles correspond with the time the parasites take to traverse …
fevers every 48 h. These fever cycles correspond with the time the parasites take to traverse …
Comparison of PvLAP5 and Pvs25 qRT-PCR assays for the detection of Plasmodium vivax gametocytes in field samples preserved at ambient temperature from …
Background As the elimination of malaria in Mesoamerica progresses, detection of
Plasmodium vivax using light microscopy (LM) becomes more difficult. Highly sensitive …
Plasmodium vivax using light microscopy (LM) becomes more difficult. Highly sensitive …
Detection of Plasmodium simium gametocytes in non-human primates from the Brazilian Atlantic Forest
LC Amaral, YEAR Salazar, DAM de Alvarenga… - Malaria Journal, 2023 - Springer
Background Plasmodium species of non-human primates (NHP) are of great interest
because they can naturally infect humans. Plasmodium simium, a parasite restricted to the …
because they can naturally infect humans. Plasmodium simium, a parasite restricted to the …
Single-cell analyses of polyclonal Plasmodium vivax infections and their consequences on parasite transmission
Most Plasmodium vivax infections contain genetically distinct parasites, but the
consequences of this polyclonality on the development of asexual parasites, their sexual …
consequences of this polyclonality on the development of asexual parasites, their sexual …
Significant number of Plasmodium vivax mono-infections by PCR misidentified as mixed infections (P. vivax/P. falciparum) by microscopy and rapid diagnostic tests …
Background Plasmodium vivax malaria is now recognized as a cause of severe morbidity
and mortality, resulting in a substantial negative effect on health especially in endemic …
and mortality, resulting in a substantial negative effect on health especially in endemic …
Transmission efficiency of Plasmodium vivax at low parasitaemia
Background Plasmodium vivax is responsible for much of malaria outside Africa. Although
most P. vivax infections in endemic areas are asymptomatic and have low parasite densities …
most P. vivax infections in endemic areas are asymptomatic and have low parasite densities …