Tumor Necrosis Factor Inhibitors for Inflammatory Bowel Disease | New England Journal of
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Ulcerative colitis (UC) has become a worldwide public health problem, and the prevalence
of the disease among children has been increasing. The pathogenesis of UC has not been …

Background Lack of evidence-based outcomes data leads to uncertainty in develo**
treatment regimens in children who are newly diagnosed with ulcerative colitis. We …

Inflammatory bowel disease (IBD) presents with disabling symptoms and may lead to
insufficient growth and late pubertal development in cases of disease onset during …

Objectives: The aim of the study was to review the evidence regarding the clinical use and
value of fecal calprotectin (FC) measurements in different gastrointestinal disorders in …

In the 1990s, tumour necrosis factor-α inhibitor therapy ushered in the biologic therapy era
for inflammatory bowel disease, leading to marked improvements in treatment options and …

Corticosteroids are the mainstay of therapy for many pediatric disorders and sometimes are
life-saving. Both endogenous and synthetic derivatives diffuse across the cell membrane …

Objectives: Colectomy rates following acute severe ulcerative colitis have plateaued around
20% despite intravenous corticosteroid and intensified anti-tumor necrosis factor (TNF) …

Background Despite the introduction of vaccination against rotavirus, and even though it can
often be treated on an outpatient basis, acute infectious gastroenteritis is nevertheless the …

Objective: To compile and synthesize the available literature describing medical cannabis
use across various disease states. Data Sources: PubMed, EBSCO, and Google Scholar …