Exosomes: a review of biologic function, diagnostic and targeted therapy applications, and clinical trials
Exosomes are extracellular vesicles generated by all cells and they carry nucleic acids,
proteins, lipids, and metabolites. They mediate the exchange of substances between cells …
proteins, lipids, and metabolites. They mediate the exchange of substances between cells …
Role of exosomes in epithelial–mesenchymal transition
Epithelial–mesenchymal transition (EMT) is a fundamental process driving cancer
metastasis, transforming non-motile cells into a motile population that migrates to distant …
metastasis, transforming non-motile cells into a motile population that migrates to distant …
The Role of Non-Coding RNAs in Epigenetic Dysregulation in Glioblastoma Development
E Isachesku, C Braicu, R Pirlog, A Kocijancic… - International Journal of …, 2023 - mdpi.com
Glioblastoma (GBM) is a primary brain tumor arising from glial cells. The tumor is highly
aggressive, the reason for which it has become the deadliest brain tumor type with the …
aggressive, the reason for which it has become the deadliest brain tumor type with the …
Immunological challenges and opportunities in glioblastoma multiforme: A comprehensive view from immune system lens
Glioblastoma multiforme (GBM), also known as grade IV astrocytoma, is the most common
and deadly brain tumour. It has a poor prognosis and a low survival rate. GBM cells' …
and deadly brain tumour. It has a poor prognosis and a low survival rate. GBM cells' …
Extracellular Vesicles in the Central Nervous System: A Novel Mechanism of Neuronal Cell Communication
Cell-to-cell communication is essential for the appropriate development and maintenance of
homeostatic conditions in the central nervous system. Extracellular vesicles have recently …
homeostatic conditions in the central nervous system. Extracellular vesicles have recently …
Advanced Nanoparticle Engineering for Precision Therapeutics of Brain Diseases
Despite the increasing global prevalence of neurological disorders, the development of
nanoparticle (NP) technologies for brain-targeted therapies confronts considerable …
nanoparticle (NP) technologies for brain-targeted therapies confronts considerable …
Harnessing the potential of nanoengineered siRNAs carriers for target responsive glioma therapy: Recent progress and future opportunities
Past scientific testimonials in the field of glioma research, the deadliest tumor among all
brain cancer types with the life span of 10-15 months after diagnosis is considered as …
brain cancer types with the life span of 10-15 months after diagnosis is considered as …
Sustainable synthesis of Cr2O3 nanoparticles utilizing Rauvolfia tetraphylla root extract for lung cancer treatment
Lung adenocarcinoma accounts for the leading cause of mortality worldwide, and it is
diagnosed only at advanced stages. Currently, existing treatment regimens including …
diagnosed only at advanced stages. Currently, existing treatment regimens including …
Silencing Exosomal circ102927 Inhibits Foot Melanoma Metastasis via Regulating Invasiveness, Epithelial-Mesenchymal Transition and Apoptosis
H Wan, L Zhong, T **a, D Zhang - Cancer Management and …, 2024 - Taylor & Francis
Background Exosomes contain abundant circular RNAs (circRNAs), playing an important
role in intercellular communication. However, the function and underlying molecular …
role in intercellular communication. However, the function and underlying molecular …
[HTML][HTML] Unlocking the Potential of Circulating miRNAs as Biomarkers in Glioblastoma
Using microRNAs (miRNAs) as potential circulating biomarkers in diagnosing and treating
glioblastoma (GBM) has garnered a lot of scientific and clinical impetus in the past decade …
glioblastoma (GBM) has garnered a lot of scientific and clinical impetus in the past decade …