The Nrf2 transcription factor governs the expression of hundreds genes involved in cell
defense against oxidative stress, the hallmark of numerous diseases such as …

The coordinating role of nuclear factor erythroid-2-related factor 2 (Nrf2) in cellular function
is undeniable. Evidence indicates that this transcription factor exerts massive regulatory …

Coronaviruses can cause serious respiratory tract infections and may also impact other end
organs such as the central nervous system, the lung and the heart. The coronavirus disease …

Respiratory viruses cause infections of the upper or lower respiratory tract and they are
responsible for the common cold—the most prevalent disease in the world. In many cases …

Transcription factor nuclear factor erythroid 2‐related factor 2 (Nrf2) is a major regulator of
antioxidant response element‐(ARE‐) driven cytoprotective protein expression. The …

Nrf2 is a transcription factor that regulates cellular redox balance and the expression of a
wide array of genes involved in immunity and inflammation, including antiviral actions. Nrf2 …

Virus‐induced oxidative stress plays a critical role in the viral life cycle as well as the
pathogenesis of viral diseases. In response to reactive oxygen species (ROS) generation by …

Oxidative stress aroused by advanced glycation-end products (AGEs) is a culprit in the
pathological progression of diabetic nephropathy. Both Sirt1 and the Keap1/Nrf2/ARE anti …

Exosomes are microvesicles known to carry biologically active molecules, including RNA,
DNA and proteins. Viral infections can induce profound changes in exosome composition …

Much more serious than the previous severe acute respiratory syndrome (SARS)
coronavirus (CoV) outbreaks, the novel SARS-CoV-2 infection has spread speedily …