African swine fever (ASF) is a viral hemorrhagic disease with exceptionally high lethality in
domestic pigs and Eurasian wild boar. Over the last decade, ASF has emerged in several …

Bacterial culture was the first method used to describe the human microbiota, but this
method is considered outdated by many researchers. Metagenomics studies have since …

Millions of new viral sequences have been identified from metagenomes, but the quality and
completeness of these sequences vary considerably. Here we present CheckV, an …

SUMMARY A pure bacterial culture remains essential for the study of its virulence, its
antibiotic susceptibility, and its genome sequence in order to facilitate the understanding …

The discovery of giant viruses, with capsids as large as some bacteria, megabase-range
genomes and a variety of traits typically found only in cellular organisms, was one of the …

Viruses and other selfish genetic elements are dominant entities in the biosphere, with
respect to both physical abundance and genetic diversity. Various selfish elements …

The discovery of eukaryotic giant viruses has transformed our understanding of the limits of
viral complexity, but the extent of their encoded metabolic diversity remains unclear. Here …

The largest known DNA viruses infect Acanthamoeba and belong to two markedly different
families. The Megaviridae exhibit pseudo-icosahedral virions up to 0.7 μm in diameter and …

Originally, viruses were defined as miniscule infectious agents that passed through filters
that retain even the smallest cells. Subsequently, viruses were considered obligate …

Viruses and mobile genetic elements are molecular parasites or symbionts that coevolve
with nearly all forms of cellular life. The route of virus replication and protein expression is …