[HTML][HTML] Properties and applications of PDMS for biomedical engineering: A review

I Miranda, A Souza, P Sousa, J Ribeiro… - Journal of functional …, 2021 - mdpi.com
Polydimethylsiloxane (PDMS) is an elastomer with excellent optical, electrical and
mechanical properties, which makes it well-suited for several engineering applications. Due …

Advances in technical assessment of spiral inertial microfluidic devices toward bioparticle separation and profiling: A critical review

M Bagi, F Amjad, SM Ghoreishian… - BioChip Journal, 2024 - Springer
Separation of micro-and nano-sized bioparticles is essential for efficient diagnostics,
chemical and biological analyses, drug development, food and chemical processing, and …

Biomedical microfluidic devices by using low-cost fabrication techniques: A review

V Faustino, SO Catarino, R Lima, G Minas - Journal of biomechanics, 2016 - Elsevier
One of the most popular methods to fabricate biomedical microfluidic devices is by using a
soft-lithography technique. However, the fabrication of the moulds to produce microfluidic …

Functional microfluidics: theory, microfabrication, and applications

M **e, Z Zhan, Y Li, J Zhao, C Zhang… - … Journal of Extreme …, 2024 - iopscience.iop.org
Microfluidic devices are composed of microchannels with a diameter ranging from ten to a
few hundred micrometers. Thus, quite a small (10− 9–10− 18 l) amount of liquid can be …

[HTML][HTML] Blood cells separation and sorting techniques of passive microfluidic devices: From fabrication to applications

SO Catarino, RO Rodrigues, D Pinho, JM Miranda… - Micromachines, 2019 - mdpi.com
Since the first microfluidic device was developed more than three decades ago, microfluidics
is seen as a technology that exhibits unique features to provide a significant change in the …

High-throughput isolation of circulating tumor cells using cascaded inertial focusing microfluidic channel

A Abdulla, W Liu, A Gholamipour-Shirazi… - Analytical …, 2018 - ACS Publications
Circulating tumor cells (CTCs) are rare cells that detach from a primary or metastasis tumor
and flow into the bloodstream. Intact and viable tumor cells are needed for genetic …

Deformation of red blood cells, air bubbles, and droplets in microfluidic devices: Flow visualizations and measurements

D Bento, RO Rodrigues, V Faustino, D Pinho… - Micromachines, 2018 - mdpi.com
Techniques, such as micropipette aspiration and optical tweezers, are widely used to
measure cell mechanical properties, but are generally labor-intensive and time-consuming …

[HTML][HTML] A microfluidic deformability assessment of pathological red blood cells flowing in a hyperbolic converging microchannel

V Faustino, RO Rodrigues, D Pinho, E Costa… - Micromachines, 2019 - mdpi.com
The loss of the red blood cells (RBCs) deformability is related with many human diseases,
such as malaria, hereditary spherocytosis, sickle cell disease, or renal diseases. Hence …

[HTML][HTML] Visualization and measurements of blood cells flowing in microfluidic systems and blood rheology: A personalized medicine perspective

D Pinho, V Carvalho, IM Gonçalves, S Teixeira… - Journal of Personalized …, 2020 - mdpi.com
Hemorheological alterations in the majority of metabolic diseases are always connected
with blood rheology disturbances, such as the increase of blood and plasma viscosity, cell …

Microfluidic solutions enabling continuous processing and monitoring of biological samples: A review

M Karle, SK Vashist, R Zengerle, F von Stetten - Analytica chimica acta, 2016 - Elsevier
The last decade has witnessed tremendous advances in employing microfluidic solutions
enabling Continuous Processing and Monitoring of Biological Samples (CPMBS), which is …