Reactive oxygen species in cancer
GY Liou, P Storz - Free radical research, 2010 - Taylor & Francis
Elevated rates of reactive oxygen species (ROS) have been detected in almost all cancers,
where they promote many aspects of tumour development and progression. However …
where they promote many aspects of tumour development and progression. However …
Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling
MD Brand - Free Radical Biology and Medicine, 2016 - Elsevier
This review examines the generation of reactive oxygen species by mammalian
mitochondria, and the status of different sites of production in redox signaling and pathology …
mitochondria, and the status of different sites of production in redox signaling and pathology …
Lipid metabolism and Alzheimer's disease: clinical evidence, mechanistic link and therapeutic promise
F Yin - The FEBS journal, 2023 - Wiley Online Library
Alzheimer's disease (AD) is an age‐associated neurodegenerative disorder with
multifactorial etiology, intersecting genetic and environmental risk factors, and a lack of …
multifactorial etiology, intersecting genetic and environmental risk factors, and a lack of …
Oxidative stress and lipid peroxidation products in cancer progression and therapy
G Barrera - International Scholarly Research Notices, 2012 - Wiley Online Library
The generation of reactive oxygen species (ROS) and an altered redox status are common
biochemical aspects in cancer cells. ROS can react with the polyunsaturated fatty acids of …
biochemical aspects in cancer cells. ROS can react with the polyunsaturated fatty acids of …
Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions
Mitochondrial production of superoxide and hydrogen peroxide is potentially important in
cell signaling and disease. Eleven distinct mitochondrial sites that differ markedly in capacity …
cell signaling and disease. Eleven distinct mitochondrial sites that differ markedly in capacity …
Oxidative stress in autism spectrum disorder
Abstract According to the United States Centers for Disease Control and Prevention (CDC),
as of July 11, 2016, the reported average incidence of children diagnosed with an autism …
as of July 11, 2016, the reported average incidence of children diagnosed with an autism …
Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism
P Ježek, L Hlavatá - The international journal of biochemistry & cell biology, 2005 - Elsevier
The recent knowledge on mitochondria as the substantial source of reactive oxygen species,
namely superoxide and hydrogen peroxide efflux from mitochondria, is reviewed, as well as …
namely superoxide and hydrogen peroxide efflux from mitochondria, is reviewed, as well as …
Oxidative stress: a common factor in testicular dysfunction
TT Turner, JJ Lysiak - Journal of andrology, 2008 - Wiley Online Library
Oxidative stress results from the production of oxygen radicals in excess of the antioxidant
capacity of the stressed tissue. Many conditions or events associated with male infertility are …
capacity of the stressed tissue. Many conditions or events associated with male infertility are …
Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs
The thioredoxin system plays a key role in regulating the overall intracellular redox balance.
It basically comprises the small redox protein thioredoxin (Trx), nicotinamide adenine …
It basically comprises the small redox protein thioredoxin (Trx), nicotinamide adenine …
Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling
Prxs (peroxiredoxins) are a family of proteins that are extremely effective at scavenging
peroxides. The Prxs exhibit a number of intriguing properties that distinguish them from …
peroxides. The Prxs exhibit a number of intriguing properties that distinguish them from …