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Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
[HTML][HTML] Current strategies for exosome cargo loading and targeting delivery
Extracellular vesicles (EVs) such as ectosomes and exosomes have gained attention as
promising natural carriers for drug delivery. Exosomes, which range from 30 to 100 nm in …
promising natural carriers for drug delivery. Exosomes, which range from 30 to 100 nm in …
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …
origin and change the functions and phenotypes of other cells. These features indicate …
A comparison of cellular uptake mechanisms, delivery efficacy, and intracellular fate between liposomes and extracellular vesicles
TB Gandek, L van der Koog… - Advanced healthcare …, 2023 - Wiley Online Library
A key aspect for successful drug delivery via lipid‐based nanoparticles is their
internalization in target cells. Two prominent examples of such drug delivery systems are …
internalization in target cells. Two prominent examples of such drug delivery systems are …
[HTML][HTML] Exosome-based drug delivery: translation from bench to clinic
HB Koh, HJ Kim, SW Kang, TH Yoo - Pharmaceutics, 2023 - mdpi.com
Exosome-based drug delivery is emerging as a promising field with the potential to
revolutionize therapeutic interventions. Exosomes, which are small extracellular vesicles …
revolutionize therapeutic interventions. Exosomes, which are small extracellular vesicles …
[HTML][HTML] Insight into extracellular vesicle-cell communication: from cell recognition to intracellular fate
Extracellular vesicles (EVs) are heterogamous lipid bilayer-enclosed membranous
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …
miR-124-3p delivered by exosomes from heme oxygenase-1 modified bone marrow mesenchymal stem cells inhibits ferroptosis to attenuate ischemia–reperfusion …
L Wu, X Tian, H Zuo, W Zheng, X Li, M Yuan… - Journal of …, 2022 - Springer
Background Steatotic livers tolerate ischemia–reperfusion injury (IRI) poorly, increasing the
risk of organ dysfunction. Ferroptosis is considered the initiating factor of organ IRI. Heme …
risk of organ dysfunction. Ferroptosis is considered the initiating factor of organ IRI. Heme …
[HTML][HTML] Preservation of biomaterials and cells by freeze-drying: Change of paradigm
Freeze-drying is the most widespread method to preserve protein drugs and vaccines in a
dry form facilitating their storage and transportation without the laborious and expensive cold …
dry form facilitating their storage and transportation without the laborious and expensive cold …
Development of extracellular vesicle therapeutics: Challenges, considerations, and opportunities
Extracellular vesicles (EVs) hold great promise as therapeutic modalities due to their
endogenous characteristics, however, further bioengineering refinement is required to …
endogenous characteristics, however, further bioengineering refinement is required to …
Iron Oxide nanoparticles Engineered macrophage-derived exosomes for targeted pathological angiogenesis therapy
Engineering exosomes with nanomaterials usually leads to the damage of exosomal
membrane and bioactive molecules. Here, pathological angiogenesis targeting exosomes …
membrane and bioactive molecules. Here, pathological angiogenesis targeting exosomes …