Blockade of brain angiotensin II AT1 receptors ameliorates stress, anxiety, brain inflammation and ischemia: therapeutic implications

JM Saavedra, E Sánchez-Lemus, J Benicky - Psychoneuroendocrinology, 2011 - Elsevier
Poor adaptation to stress, alterations in cerebrovascular function and excessive brain
inflammation play critical roles in the pathophysiology of many psychiatric and neurological …

Brain and pituitary angiotensin

JM Saavedra - Endocrine reviews, 1992 - academic.oup.com
I. Introduction A ngiotensin (ANG II) was discovered about 50 yr ago (1, 2), and a complete
peripheral system for the formation and metabolism of ANG II was soon characterized. It was …

Neurophysiology and neuropharmacology of hypothalamic magnocellular neurons secreting vasopressin and oxytocin

LP Renaud, CW Bourquet - Progress in neurobiology, 1991 - Elsevier
2.1. 1. Oxytocin-secreting cells 2.1. 2. Vasopressin-secreting cells 2.1. 3. Firing patterns and
hormone release 2.2. Intrinsic properties 2.2. 1. Action potentials 2.2. 2. Hyperpolarizing …

The hypothalamus and hypertension

HE De Wardener - Physiological reviews, 2001 - journals.physiology.org
Most forms of hypertension are associated with a wide variety of functional changes in the
hypothalamus. Alterations in the following substances are discussed: catecholamines …

Angiotensin II in central nervous system physiology

MI Phillips, C Sumners - Regulatory peptides, 1998 - Elsevier
1. Introduction direct injection of Ang II into the rat brain produced drinking behavior [9] and
indirect measurements showing Exactly one hundred years ago Tiegerstedt and Bergman …

Physiology and pathophysiology of atrial peptides

KL Goetz - American Journal of Physiology-Endocrinology …, 1988 - journals.physiology.org
The atria secrete atrial peptides (atriopeptins) that are capable of producing dramatic
alterations in a number of body processes. Secretion of atriopeptin appears to be regulated …

Natriuretic peptides in vascular physiology and pathology

GE Woodard, JA Rosado - International review of cell and molecular …, 2008 - Elsevier
Four major natriuretic peptides have been isolated: atrial natriuretic peptide (ANP), brain
natriuretic peptide (BNP), C‐type natriuretic peptide (CNP), and Dendroaspis‐type …

Brain renin-angiotensin system in the pathophysiology of cardiovascular diseases

G Huber, F Schuster, W Raasch - Pharmacological research, 2017 - Elsevier
Cardiovascular diseases (CVD) are among the main causes of death globally and in this
context hypertension represents one of the key risk factors for develo** a CVD. It is well …

Actions of angiotensin in the subfornical organ and area postrema: implications for long term control of autonomic output

AV Ferguson, JS Bains - Clinical and experimental …, 1997 - Wiley Online Library
Considerable physiological and anatomical evidence indicates that circulating angiotensin II
(AngII), plays important roles in the long‐term regulation of autonomic output as a result of …

Electrophysiology of the circumventricular organs

AV Ferguson, JS Bains - Frontiers in neuroendocrinology, 1996 - Elsevier
Since the first anatomical description of the circumventricular organs (CVOs) as a structurally
distinct group of regions in the central nervous system (CNS), considerable information has …