Global Literature Analysis of Organoid and Organ‐on‐Chip Research
Organoids and cells in organ‐on‐chip platforms replicate higher‐level anatomical,
physiological, or pathological states of tissues and organs. These technologies are widely …
physiological, or pathological states of tissues and organs. These technologies are widely …
Revisiting airflow and aerosol transport phenomena in the deep lungs with microfluidics
J Sznitman - Chemical Reviews, 2021 - ACS Publications
The dynamics of respiratory airflows and the associated transport mechanisms of inhaled
aerosols characteristic of the deep regions of the lungs are of broad interest in assessing …
aerosols characteristic of the deep regions of the lungs are of broad interest in assessing …
A biomimetic human Lung‐on‐a‐Chip with colorful display of microphysiological breath
Lung‐on‐a‐chip models hold great promise for disease modeling and drug screening.
Herein, inspired by the iridescence phenomenon of soap bubbles, a novel biomimetic 3D …
Herein, inspired by the iridescence phenomenon of soap bubbles, a novel biomimetic 3D …
3D inkjet-bioprinted lung-on-a-chip
There is an urgent need for physiologically relevant and customizable biochip models of
human lung tissue to provide a niche for lung disease modeling and drug efficacy. Although …
human lung tissue to provide a niche for lung disease modeling and drug efficacy. Although …
Biomimetic in vitro lung models: current challenges and future perspective
As post‐COVID complications, chronic respiratory diseases are one of the foremost causes
of mortality. The quest for a cure for this recent global challenge underlines that the lack of …
of mortality. The quest for a cure for this recent global challenge underlines that the lack of …
Understanding fibroblast-immune cell interactions via co-culture models and their role in asthma pathogenesis
F Thiam, SA Yazeedi, K Feng, S Phogat… - Frontiers in …, 2023 - frontiersin.org
Asthma is a chronic lung disease involving airway inflammation and fibrosis. Fibroblasts are
the main effector cells important for lung tissue production which becomes abnormal in …
the main effector cells important for lung tissue production which becomes abnormal in …
A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chip
A Sengupta, A Dorn, M Jamshidi, M Schwob… - Frontiers in …, 2023 - frontiersin.org
Prolonged exposure to environmental respirable toxicants can lead to the development and
worsening of severe respiratory diseases such as asthma, chronic obstructive pulmonary …
worsening of severe respiratory diseases such as asthma, chronic obstructive pulmonary …
[HTML][HTML] Human lung cell models to study aerosol delivery–Considerations for model design and development
B Rothen-Rutishauser, M Gibb, R He… - European Journal of …, 2023 - Elsevier
Human lung tissue models range from simple monolayer cultures to more advanced three-
dimensional co-cultures. Each model system can address the interactions of different types …
dimensional co-cultures. Each model system can address the interactions of different types …
An In Vitro Microfluidic Alveolus Model to Study Lung Biomechanics
The gas exchange units of the lung, the alveoli, are mechanically active and undergo cyclic
deformation during breathing. The epithelial cells that line the alveoli contribute to lung …
deformation during breathing. The epithelial cells that line the alveoli contribute to lung …
Unravelling the molecular mechanisms underlying chronic respiratory diseases for the development of novel therapeutics via in vitro experimental models
Chronic respiratory diseases have collectively become a major public health concern and
have now taken form as one of the leading causes of mortality worldwide. Most chronic …
have now taken form as one of the leading causes of mortality worldwide. Most chronic …