[PDF][PDF] Sex differences in nonalcoholic fatty liver disease: state of the art and identification of research gaps

A Lonardo, F Nascimbeni, S Ballestri… - …, 2019 - Wiley Online Library
Despite tremendous research advancements in nonalcoholic fatty liver disease (NAFLD),
our understanding of sex differences in NAFLD remains insufficient. This review summarizes …

[HTML][HTML] Sexual dimorphism of NAFLD in adults. Focus on clinical aspects and implications for practice and translational research

A Lonardo, A Suzuki - Journal of clinical medicine, 2020 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) embraces the clinico-pathological consequences
of hepatic lipotoxicity and is a major public health problem globally. Sexual dimorphism is a …

Associations between dietary flavonoid intake with hepatic steatosis and fibrosis quantified by VCTE: evidence from NHANES and FNDDS

R **e, Y Zhang - Nutrition, Metabolism and Cardiovascular Diseases, 2023 - Elsevier
Background and aim Flavonoids are natural products of plant origin and have been shown
to be beneficial for nonalcoholic fatty liver disease (NAFLD) in animal studies. However …

Formyl peptide receptor 2 determines sex-specific differences in the progression of nonalcoholic fatty liver disease and steatohepatitis

C Lee, J Kim, J Han, D Oh, M Kim, H Jeong… - Nature …, 2022 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is an important health concern worldwide and
progresses into nonalcoholic steatohepatitis (NASH). Although prevalence and severity of …

[PDF][PDF] Bone morphogenetic protein 9 is a paracrine factor controlling liver sinusoidal endothelial cell fenestration and protecting against hepatic fibrosis

A Desroches‐Castan, E Tillet, N Ricard, M Ouarné… - …, 2019 - Wiley Online Library
Bone morphogenetic protein 9 (BMP9) is a circulating factor produced by hepatic stellate
cells that plays a critical role in vascular quiescence through its endothelial receptor activin …

Early prediction of incident liver disease using conventional risk factors and gut-microbiome-augmented gradient boosting

Y Liu, G Meric, AS Havulinna, SM Teo, F Åberg… - Cell Metabolism, 2022 - cell.com
The gut microbiome has shown promise as a predictive biomarker for various diseases.
However, the potential of gut microbiota for prospective risk prediction of liver disease has …

Cullin-associated and neddylation-dissociated protein 1 (CAND1) alleviates NAFLD by reducing ubiquitinated degradation of ACAA2

X Huang, X Liu, X Li, Y Zhang, J Gao, Y Yang… - Nature …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disorder with high
morbidity and mortality. The current study aims to explore the role of Cullin-associated and …

[HTML][HTML] Comprehensive review of cardiovascular disease risk in nonalcoholic fatty liver disease

K Josloff, J Beiriger, A Khan, RJ Gawel… - Journal of …, 2022 - mdpi.com
Nonalcoholic Fatty Liver Disease (NAFLD) is a growing global phenomenon, and its
damaging effects in terms of cardiovascular disease (CVD) risk are becoming more …

Butyrate attenuates hepatic steatosis induced by a high‐fat and fiber‐deficient diet via the hepatic GPR41/43‐CaMKII/HDAC1‐CREB pathway

M Zheng, X Yang, Q Wu, Y Gong… - Molecular Nutrition & …, 2023 - Wiley Online Library
Scope Hepatic steatosis is a major health issue that can be attenuated by a healthy diet.
This study investigates the effects and molecular mechanisms of butyrate, a dietary fiber …

Characteristic features of nonalcoholic fatty liver disease in Japan with a focus on the roles of age, sex and body mass index

M Tobari, E Hashimoto - Gut and Liver, 2020 - pmc.ncbi.nlm.nih.gov
This review provides an update on the characteristics of nonalcoholic fatty liver disease
(NAFLD), with a focus on the effects of age, sex, and body mass index. Age is a risk factor for …