Transcription is a central aspect of DNA metabolism that takes place on the same substrate
as replication, repair and recombination Not surprisingly, therefore, there is a physical and …

Active host-pathogen interactions take place during infection of human immunodeficiency
virus type 1 (HIV-1). Outcomes of these interactions determine the efficiency of viral infection …

NELF and DSIF collaborate to inhibit elongation by RNA polymerase IIa in extracts from
human cells. A multifaceted approach was taken to investigate the potential role of these …

Peroxisome proliferator-activated receptor γ (PPARγ) gained considerable interest as a
therapeutic target during chronic inflammatory diseases. Remarkably, the pathogenesis of …

Cold, hyperosmolarity, and abscisic acid (ABA) signaling induce RD29A expression, which
is an indicator of the plant stress adaptation response. Two nonallelic Arabidopsis thaliana …

In this study, we describe a property of Gramineae genes, and perhaps all monocot genes,
that is not observed in eudicot genes. Along the direction of transcription, beginning at the …

We report a" running start, two-bond" protocol to analyze elongation by human RNA
polymerase II (RNAP II). In this procedure, the running start allowed us to measure rapid …

There are nine genetic neurodegenerative diseases caused by a similar genetic defect, a
CAG DNA triplet-repeat expansion in the disease gene's open reading frame resulting in a …

ABSTRACT ICP22 is a multifunctional herpes simplex virus 1 (HSV-1) regulatory protein that
regulates the accumulation of a subset of late (γ2) proteins exemplified by UL38, UL41, and …

As the first systematic examination of simple sequence repeats (SSRs) and guanine-
cytosine (GC) distribution in intragenic and intergenic regions of ten primates, our study …