Photocatalytic late-stage C–H functionalization

P Bellotti, HM Huang, T Faber, F Glorius - Chemical Reviews, 2023 - ACS Publications
The emergence of modern photocatalysis, characterized by mildness and selectivity, has
significantly spurred innovative late-stage C–H functionalization approaches that make use …

[HTML][HTML] Towards the sustainable discovery and development of new antibiotics

M Miethke, M Pieroni, T Weber, M Brönstrup… - Nature Reviews …, 2021 - nature.com
An ever-increasing demand for novel antimicrobials to treat life-threatening infections
caused by the global spread of multidrug-resistant bacterial pathogens stands in stark …

Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers

P Peluso, B Chankvetadze - Chemical Reviews, 2022 - ACS Publications
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

Halogen bonding in supramolecular chemistry

LC Gilday, SW Robinson, TA Barendt… - Chemical …, 2015 - ACS Publications
Supramolecular chemistry is “the chemistry of the intermolecular bond, covering the
structures and functions of the entities formed by association of two or more chemical …

Halogen, Chalcogen, Pnictogen, and Tetrel Bonding in Non‐Covalent Organocatalysis: An Update

D Jovanovic, M Poliyodath Mohanan… - Angewandte Chemie …, 2024 - Wiley Online Library
The use of noncovalent interactions based on electrophilic halogen, chalcogen, pnictogen,
or tetrel centers in organocatalysis has gained noticeable attention. Herein, we provide an …

Chitosan-based Schiff bases: Promising materials for biomedical and industrial applications

V Pawariya, S De, J Dutta - Carbohydrate Polymers, 2024 - Elsevier
There is plenty of scope for modifying chitosan, an only polycationic natural polysaccharide,
owing to its reactive functional groups, namely hydroxyl and amino groups. Although …

Catalysis of organic reactions through halogen bonding

RL Sutar, SM Huber - ACS Catalysis, 2019 - ACS Publications
Halogen bonding, the noncovalent interaction based on electrophilic halogen substituents,
features very interesting properties, as illustrated by numerous applications continuously …

The most common functional groups in bioactive molecules and how their popularity has evolved over time

P Ertl, E Altmann, JM McKenna - Journal of medicinal chemistry, 2020 - ACS Publications
The concept of functional groups (FGs), sets of connected atoms that can determine the
intrinsic reactivity of the parent molecule and in part are responsible for the overall …

A survey of the role of noncovalent sulfur interactions in drug design

BR Beno, KS Yeung, MD Bartberger… - Journal of medicinal …, 2015 - ACS Publications
Electron deficient, bivalent sulfur atoms have two areas of positive electrostatic potential, a
consequence of the low-lying σ* orbitals of the C–S bond that are available for interaction …

Computer modeling of halogen bonds and other σ-hole interactions

MH Kolar, P Hobza - Chemical reviews, 2016 - ACS Publications
In the field of noncovalent interactions a new paradigm has recently become popular. It
stems from the analysis of molecular electrostatic potentials and introduces a label, which …