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A dynamic DNA tetrahedron framework for active targeting
An active targeting strategy-enabled DNA tetrahedron delivery vehicle could facilitate stable
drug encapsulation and stimuli-responsive on-demand release, building a universal …
drug encapsulation and stimuli-responsive on-demand release, building a universal …
DNA origami
Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …
Biomimetic nanoerythrosome‐coated aptamer–DNA tetrahedron/maytansine conjugates: pH‐responsive and targeted cytotoxicity for HER2‐positive breast cancer
W Ma, Y Yang, J Zhu, W Jia, T Zhang, Z Liu… - Advanced …, 2022 - Wiley Online Library
DNA materials have emerged as potential nanocarriers for targeted cancer therapy to
precisely deliver cargos with specific purposes. The short half‐life and low bioavailability of …
precisely deliver cargos with specific purposes. The short half‐life and low bioavailability of …
Photocleavable Ortho-Nitrobenzyl-Protected DNA Architectures and Their Applications
This review article introduces mechanistic aspects and applications of photochemically
deprotected ortho-nitrobenzyl (ONB)-functionalized nucleic acids and their impact on …
deprotected ortho-nitrobenzyl (ONB)-functionalized nucleic acids and their impact on …
The biological applications of DNA nanomaterials: current challenges and future directions
W Ma, Y Zhan, Y Zhang, C Mao, X **e… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …
biological applications as driven by DNA nanotechnology in the past decades, including …
Prospects and challenges of dynamic DNA nanostructures in biomedical applications
T Tian, Y Li, Y Lin - Bone Research, 2022 - nature.com
The physicochemical nature of DNA allows the assembly of highly predictable structures via
several fabrication strategies, which have been applied to make breakthroughs in various …
several fabrication strategies, which have been applied to make breakthroughs in various …
Principles and applications of nucleic acid strand displacement reactions
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the
study and application of nucleic acid strand-displacement reactions. Strand-displacement …
study and application of nucleic acid strand-displacement reactions. Strand-displacement …
DNA nanotechnology-enabled drug delivery systems
Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …
Nuclease resistance of DNA nanostructures
AR Chandrasekaran - Nature Reviews Chemistry, 2021 - nature.com
DNA nanotechnology has progressed from proof-of-concept demonstrations of structural
design towards application-oriented research. As a natural material with excellent self …
design towards application-oriented research. As a natural material with excellent self …
DNA origami: scaffolds for creating higher order structures
DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …