[HTML][HTML] From machine learning to deep learning: Advances of the recent data-driven paradigm shift in medicine and healthcare

C Chakraborty, M Bhattacharya, S Pal… - Current Research in …, 2024 - Elsevier
The medicine and healthcare sector has been evolving and advancing very fast. The
advancement has been initiated and shaped by the applications of data-driven, robust, and …

Accelerating biocatalysis discovery with machine learning: a paradigm shift in enzyme engineering, discovery, and design

B Markus, K Andreas, K Arkadij, L Stefan, O Gustav… - ACS …, 2023 - ACS Publications
Emerging computational tools promise to revolutionize protein engineering for biocatalytic
applications and accelerate the development timelines previously needed to optimize an …

Protein–protein contact prediction by geometric triangle-aware protein language models

P Lin, H Tao, H Li, SY Huang - Nature Machine Intelligence, 2023 - nature.com
Abstract Information regarding the residue–residue distance between interacting proteins is
important for modelling the structures of protein complexes, as well as being valuable for …

Open-source machine learning in computational chemistry

A Hagg, KN Kirschner - Journal of Chemical Information and …, 2023 - ACS Publications
The field of computational chemistry has seen a significant increase in the integration of
machine learning concepts and algorithms. In this Perspective, we surveyed 179 open …

Targeted protein degradation: current and emerging approaches for E3 ligase deconvolution

Y **ao, Y Yuan, Y Liu, Z Lin, G Zheng… - Journal of Medicinal …, 2024 - ACS Publications
Targeted protein degradation (TPD), including the use of proteolysis-targeting chimeras
(PROTACs) and molecular glue degraders (MGDs) to degrade proteins, is an emerging …

Plant-based proteins: advanced extraction technologies, interactions, physicochemical and functional properties, food and related applications, and health benefits

AK Rashwan, AI Osman, AM Abdelshafy… - Critical Reviews in …, 2023 - Taylor & Francis
Even though plant proteins are more plentiful and affordable than animal proteins in
comparison, direct usage of plant-based proteins (PBPs) is still limited because PBPs are …

HNSPPI: a hybrid computational model combing network and sequence information for predicting protein–protein interaction

S **e, X **e, X Zhao, F Liu, Y Wang… - Briefings in …, 2023 - academic.oup.com
Most life activities in organisms are regulated through protein complexes, which are mainly
controlled via Protein–Protein Interactions (PPIs). Discovering new interactions between …

Enhancing of transport parameters and antifouling properties of PVDF membranes modified with Fe3O4 nanoparticles in the process of proteins fractionation

H Bubela, V Konovalova, J Kujawa, I Kolesnyk… - Separation and …, 2023 - Elsevier
Polyvinylidene fluoride (PVDF) possesses a broad range of applications, including
membrane separation used for water and wastewater treatment. However, the natural …

[HTML][HTML] ProtInteract: A deep learning framework for predicting protein–protein interactions

F Soleymani, E Paquet, HL Viktor… - Computational and …, 2023 - Elsevier
Proteins mainly perform their functions by interacting with other proteins. Protein–protein
interactions underpin various biological activities such as metabolic cycles, signal …

Cracking the black box of deep sequence-based protein–protein interaction prediction

J Bernett, DB Blumenthal, M List - Briefings in Bioinformatics, 2024 - academic.oup.com
Identifying protein–protein interactions (PPIs) is crucial for deciphering biological pathways.
Numerous prediction methods have been developed as cheap alternatives to biological …