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The structure and mechanism of the bacterial type II secretion system
The type II secretion system (T2SS) is a multi‐protein complex used by many bacteria to
move substrates across their cell membrane. Substrates released into the environment …
move substrates across their cell membrane. Substrates released into the environment …
Bacterial secretins: mechanisms of assembly and membrane targeting
Secretion systems are employed by bacteria to transport macromolecules across
membranes without compromising their integrities. Processes including virulence …
membranes without compromising their integrities. Processes including virulence …
Assembly mechanism of a Tad secretion system secretin-pilotin complex
The bacterial T ight ad herence S ecretion S ystem (TadSS) assembles surface pili that drive
cell adherence, biofilm formation and bacterial predation. The structure and mechanism of …
cell adherence, biofilm formation and bacterial predation. The structure and mechanism of …
In vivo structure of the Legionella type II secretion system by electron cryotomography
The type II secretion system (T2SS) is a multiprotein envelope-spanning assembly that
translocates a wide range of virulence factors, enzymes and effectors through the outer …
translocates a wide range of virulence factors, enzymes and effectors through the outer …
CryoEM structure of the type IVa pilus secretin required for natural competence in Vibrio cholerae
Natural transformation is the process by which bacteria take up genetic material from their
environment and integrate it into their genome by homologous recombination. It represents …
environment and integrate it into their genome by homologous recombination. It represents …
Insights into dynamics and gating properties of T2SS secretins
Secretins are outer membrane (OM) channels found in various bacterial nanomachines that
secrete or assemble large extracellular structures. High-resolution 3D structures of type 2 …
secrete or assemble large extracellular structures. High-resolution 3D structures of type 2 …
Structural lessons on bacterial secretins
To exchange and communicate with their surroundings, bacteria have evolved multiple
active and passive mechanisms for trans-envelope transport. Among the pore-forming …
active and passive mechanisms for trans-envelope transport. Among the pore-forming …
Cold shock proteins improve E. coli cell‐free synthesis in terms of soluble yields of aggregation‐prone proteins
K Higuchi, T Yabuki, M Ito… - Biotechnology and …, 2020 - Wiley Online Library
Protein folding is usually slowed‐down at low temperatures, and thus low‐temperature
expression is an effective strategy to improve the soluble yield of aggregation‐prone …
expression is an effective strategy to improve the soluble yield of aggregation‐prone …
Role of bacterial secretion systems and effector proteins–insights into Aeromonas pathogenicity mechanisms
J Matys, A Turska-Szewczuk… - Acta Biochimica …, 2020 - abp.ptbioch.edu.pl
Gram-negative bacteria have developed several nanomachine channels known as type II,
III, IV and VI secretion systems that enable export of effector proteins/toxins from the cytosol …
III, IV and VI secretion systems that enable export of effector proteins/toxins from the cytosol …
Comparative transcriptome and phenotype analysis revealed the role and mechanism of ompR in the virulence of fish pathogenic Aeromonas hydrophila
M Zhang, J Kang, B Wu, Y Qin, L Huang… - …, 2020 - Wiley Online Library
Aeromonas hydrophila B11 strain was isolated from diseased Anguilla japonica, which had
caused severe gill ulcers in farmed eel, causing huge economic losses. EnvZ‐OmpR is a …
caused severe gill ulcers in farmed eel, causing huge economic losses. EnvZ‐OmpR is a …