The term fibroblast has been used generally to describe spindle-shaped stromal cells of
mesenchymal origin that produce extracellular matrix, establish tissue structure, and form …

Klebsiella pneumoniae is among the most common antibiotic-resistant pathogens causing
nosocomial infections. Additionally, it is a leading cause of neonatal sepsis and childhood …

Alcohol-associated liver disease is accompanied by intestinal mycobiome dysbiosis, yet the
impacts on liver disease are unclear. We demonstrate that Candida albicans-specific T …

The skin provides an essential barrier for host defense through rapid action of multiple
resident and recruited cell types, but the complex communication network governing these …

Rapid reaction to microbes invading mucosal tissues is key to protect the host against
disease. Respiratory tissue‐resident memory T (TRM) cells provide superior immunity …

Enterotoxin adjuvants have been researched for their ability to promote immunity to co-
delivered antigens. Outside of cholera vaccines, however, these proteins have yet to be …

Background Neutrophil extracellular traps (NETs) play an important role in the development
and progression of ulcerative colitis (UC). Peptidyl arginine deiminase 4 (PAD4) is essential …

Objectives The multidrug-resistant bacteria Acinetobacter baumannii is a major cause of
hospital-associated infection; a vaccine could significantly reduce this burden. The aim was …

The global burden of infections due to the pathogenic fungus Cryptococcus is substantial in
persons with low CD4+ T-cell counts. Previously, we deleted three chitin deacetylase genes …

Mucosally active subunit vaccines are an unmet clinical need due to lack of licensed
immunostimulants suitable for vaccine antigens. Here, we show that intranasal …