The ménage à trois of autophagy, lipid droplets and liver disease

Y Filali-Mouncef, C Hunter, F Roccio, S Zagkou… - Autophagy, 2022 - Taylor & Francis
Autophagic pathways cross with lipid homeostasis and thus provide energy and essential
building blocks that are indispensable for liver functions. Energy deficiencies are …

Potential role of flavonoids in treating chronic inflammatory diseases with a special focus on the anti-inflammatory activity of apigenin

R Ginwala, R Bhavsar, DGI Chigbu, P Jain, ZK Khan - Antioxidants, 2019 - mdpi.com
Inflammation has been reported to be intimately linked to the development or worsening of
several non-infectious diseases. A number of chronic conditions such as cancer, diabetes …

Mitochondrial dysfunction plays central role in nonalcoholic fatty liver disease

R Ramanathan, AH Ali, JA Ibdah - International Journal of Molecular …, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is a global pandemic that affects one-quarter of the
world's population. NAFLD includes a spectrum of progressive liver disease from steatosis to …

[HTML][HTML] The bidirectional immune crosstalk in metabolic dysfunction-associated steatotic liver disease

K Sawada, H Chung, S Softic, ME Moreno-Fernandez… - Cell Metabolism, 2023 - cell.com
Metabolic dysfunction-associated steatotic liver disease (MASLD) is an unabated risk factor
for end-stage liver diseases with no available therapies. Dysregulated immune responses …

Vitamin A signaling and homeostasis in obesity, diabetes, and metabolic disorders

WS Blaner - Pharmacology & therapeutics, 2019 - Elsevier
Much evidence has accumulated in the literature over the last fifteen years that indicates
vitamin A has a role in metabolic disease prevention and causation. This literature proposes …

Mitochondrial dysfunction-related lipid changes occur in nonalcoholic fatty liver disease progression

KY Peng, MJ Watt, S Rensen, JW Greve, K Huynh… - Journal of lipid …, 2018 - ASBMB
Nonalcoholic fatty liver disease (NAFLD) comprises fat-accumulating conditions within
hepatocytes that can cause severe liver damage and metabolic comorbidities. Studies …

Relationship between heart disease and liver disease: a two-way street

H El Hadi, A Di Vincenzo, R Vettor, M Rossato - Cells, 2020 - mdpi.com
In clinical practice, combined heart and liver dysfunctions coexist in the setting of the main
heart and liver diseases because of complex cardiohepatic interactions. It is becoming …

Race and ethnicity in non-alcoholic fatty liver disease (NAFLD): a narrative review

K Riazi, MG Swain, SE Congly, GG Kaplan… - Nutrients, 2022 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a significant public health concern worldwide
with a complex etiology attributed to behavioural, environmental, and genetic causes. The …

[HTML][HTML] Metabolic aspects of adult patients with nonalcoholic fatty liver disease

L Abenavoli, N Milic, L Di Renzo… - World journal of …, 2016 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease and it
encompasses a spectrum from simple steatosis to steatohepatitis, fibrosis, or cirrhosis. The …

[HTML][HTML] Nonalcoholic fatty liver disease: an emerging modern-day risk factor for cardiovascular disease

G Hassen, A Singh, G Belete, N Jain, I De la Hoz… - Cureus, 2022 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD), also named metabolic dysfunction-associated fatty
liver disease (MAFLD), is a progressive disease spectrum encompassing simple steatosis …