Double-membrane vesicles as platforms for viral replication

G Wolff, CE Melia, EJ Snijder, M Bárcena - Trends in microbiology, 2020 - cell.com
Viruses, as obligate intracellular parasites, exploit cellular pathways and resources in a
variety of fascinating ways. A striking example of this is the remodelling of intracellular …

The role of autophagy in viral infections

T Chen, S Tu, L Ding, M **, H Chen, H Zhou - Journal of biomedical …, 2023 - Springer
Autophagy is an evolutionarily conserved catabolic cellular process that exerts antiviral
functions during a viral invasion. However, co-evolution and co-adaptation between viruses …

A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis

EJ Snijder, RWAL Limpens, AH de Wilde… - PLoS …, 2020 - journals.plos.org
Zoonotic coronavirus (CoV) infections, such as those responsible for the current severe
acute respiratory syndrome-CoV 2 (SARS-CoV-2) pandemic, cause grave international …

Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators

SSG Dias, VC Soares, AC Ferreira… - PLoS …, 2020 - journals.plos.org
Viruses are obligate intracellular parasites that make use of the host metabolic machineries
to meet their biosynthetic needs. Thus, identifying the host pathways essential for the virus …

The double-membrane vesicle (DMV): a virus-induced organelle dedicated to the replication of SARS-CoV-2 and other positive-sense single-stranded RNA viruses

P Roingeard, S Eymieux, J Burlaud-Gaillard… - Cellular and Molecular …, 2022 - Springer
Positive single-strand RNA (+ RNA) viruses can remodel host cell membranes to induce a
replication organelle (RO) isolating the replication of their genome from innate immunity …

Noroviruses—the state of the art, nearly fifty years after their initial discovery

LF Ludwig-Begall, A Mauroy, E Thiry - Viruses, 2021 - mdpi.com
Human noroviruses are recognised as the major global cause of viral gastroenteritis. Here,
we provide an overview of notable advances in norovirus research and provide a short …

[HTML][HTML] Metformin suppresses SARS-CoV-2 in cell culture

H Parthasarathy, D Tandel, AH Siddiqui, KH Harshan - Virus research, 2023 - Elsevier
Comorbidities such as diabetes worsen COVID-19 severity and recovery. Metformin, a first-
line medication for type 2 diabetes, has antiviral properties and certain studies have also …

Fat, fight, and beyond: The multiple roles of lipid droplets in infections and inflammation

FS Pereira-Dutra, L Teixeira… - Journal of leukocyte …, 2019 - academic.oup.com
Increased accumulation of cytoplasmic lipid droplets (LDs) in host nonadipose cells is
commonly observed in response to numerous infectious diseases, including bacterial …

Caliciviridae Other Than Noroviruses

U Desselberger - Viruses, 2019 - mdpi.com
Besides noroviruses, the Caliciviridae family comprises four other accepted genera:
Sapovirus, Lagovirus, Vesivirus, and Nebovirus. There are six new genera proposed …

Human norovirus proteins: implications in the replicative cycle, pathogenesis, and the host immune response

CP Campillay-Véliz, JJ Carvajal… - Frontiers in …, 2020 - frontiersin.org
Human noroviruses (HuNoVs) are the cause of more than 95% of epidemic non-bacterial
gastroenteritis worldwide, with some lethal cases. These viral agents affect people of all …