Considering sex as a biological variable will require a global shift in science culture
For over half a century, male rodents have been the default model organism in preclinical
neuroscience research, a convention that has likely contributed to higher rates of …
neuroscience research, a convention that has likely contributed to higher rates of …
Towards the fully automated monitoring of ecological communities
High‐resolution monitoring is fundamental to understand ecosystems dynamics in an era of
global change and biodiversity declines. While real‐time and automated monitoring of …
global change and biodiversity declines. While real‐time and automated monitoring of …
Keypoint-MoSeq: parsing behavior by linking point tracking to pose dynamics
Keypoint tracking algorithms can flexibly quantify animal movement from videos obtained in
a wide variety of settings. However, it remains unclear how to parse continuous keypoint …
a wide variety of settings. However, it remains unclear how to parse continuous keypoint …
Survey of spiking in the mouse visual system reveals functional hierarchy
The anatomy of the mammalian visual system, from the retina to the neocortex, is organized
hierarchically. However, direct observation of cellular-level functional interactions across this …
hierarchically. However, direct observation of cellular-level functional interactions across this …
Multi-animal pose estimation, identification and tracking with DeepLabCut
Estimating the pose of multiple animals is a challenging computer vision problem: frequent
interactions cause occlusions and complicate the association of detected keypoints to the …
interactions cause occlusions and complicate the association of detected keypoints to the …
[HTML][HTML] Large-scale two-photon calcium imaging in freely moving mice
We developed a miniaturized two-photon microscope (MINI2P) for fast, high-resolution,
multiplane calcium imaging of over 1,000 neurons at a time in freely moving mice. With a …
multiplane calcium imaging of over 1,000 neurons at a time in freely moving mice. With a …
Deep learning tools for the measurement of animal behavior in neuroscience
Highlights•Deep neural networks are shattering performance benchmarks in computer
vision for various tasks.•Using modern deep learning approaches (DNNs) in the lab is a …
vision for various tasks.•Using modern deep learning approaches (DNNs) in the lab is a …
DeepPoseKit, a software toolkit for fast and robust animal pose estimation using deep learning
Quantitative behavioral measurements are important for answering questions across
scientific disciplines—from neuroscience to ecology. State-of-the-art deep-learning methods …
scientific disciplines—from neuroscience to ecology. State-of-the-art deep-learning methods …
A non-hallucinogenic LSD analog with therapeutic potential for mood disorders
Hallucinations limit widespread therapeutic use of psychedelics as rapidly acting
antidepressants. Here we profiled the non-hallucinogenic lysergic acid diethylamide (LSD) …
antidepressants. Here we profiled the non-hallucinogenic lysergic acid diethylamide (LSD) …
Fatigue-resistant hydrogel optical fibers enable peripheral nerve optogenetics during locomotion
We develop soft and stretchable fatigue-resistant hydrogel optical fibers that enable
optogenetic modulation of peripheral nerves in naturally behaving animals during persistent …
optogenetic modulation of peripheral nerves in naturally behaving animals during persistent …