The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty

L Ferrucci, E Fabbri - Nature Reviews Cardiology, 2018 - nature.com
Most older individuals develop inflammageing, a condition characterized by elevated levels
of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability …

[HTML][HTML] The central nervous system and the gut microbiome

G Sharon, TR Sampson, DH Geschwind… - Cell, 2016 - cell.com
Neurodevelopment is a complex process governed by both intrinsic and extrinsic signals.
While historically studied by researching the brain, inputs from the periphery impact many …

Gut microbiota composition correlates with diet and health in the elderly

MJ Claesson, IB Jeffery, S Conde, SE Power… - Nature, 2012 - nature.com
Alterations in intestinal microbiota composition are associated with several chronic
conditions, including obesity and inflammatory diseases. The microbiota of older people …

Colonic bacterial composition in Parkinson's disease

A Keshavarzian, SJ Green, PA Engen… - Movement …, 2015 - Wiley Online Library
Abstract Introduction We showed that Parkinson's disease (PD) patients have alpha‐
synuclein (α‐Syn) aggregation in their colon with evidence of colonic inflammation. If PD …

Understanding the gut microbiota and sarcopenia: a systematic review

C Liu, WH Cheung, J Li, SKH Chow… - Journal of cachexia …, 2021 - Wiley Online Library
Background Gut microbiota dysbiosis and sarcopenia commonly occur in the elderly.
Although the concept of the gut–muscle axis has been raised, the casual relationship is still …

The role of nutrition in inflammaging

P Di Giosia, CA Stamerra, P Giorgini… - Ageing research …, 2022 - Elsevier
Background Old age is characterized by a peculiar low-grade, chronic, and “sterile”
inflammatory state, which has been termed “inflammaging.” This is believed to substantially …

The gut microbiota and unhealthy aging: disentangling cause from consequence

EN DeJong, MG Surette, DME Bowdish - Cell Host & Microbe, 2020 - cell.com
The gut microbiota changes with age, but it is not clear to what degree these changes are
due to physiologic changes, age-associated inflammation or immunosenescence, diet …

The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age

D Mariat, O Firmesse, F Levenez, VD Guimarăes… - BMC microbiology, 2009 - Springer
Background In humans, the intestinal microbiota plays an important role in the maintenance
of host health by providing energy, nutrients, and immunological protection. Applying current …

Gut bifidobacteria populations in human health and aging

S Arboleya, C Watkins, C Stanton… - Frontiers in microbiology, 2016 - frontiersin.org
The intestinal microbiota has increasingly been shown to have a vital role in various aspects
of human health. Indeed, several studies have linked alterations in the gut microbiota with …