NXPH4 mediated by m5C contributes to the malignant characteristics of colorectal cancer via inhibiting HIF1A degradation

L Yang, J Shi, M Zhong, P Sun, X Zhang, Z Lian… - Cellular & Molecular …, 2024 - Springer
Objective Colorectal cancer (CRC) is a form of malignancy that exhibits a comparatively
elevated occurrence and fatality rate. Given the relatively slower progress in diagnostic and …

Tangshen formula protects against podocyte apoptosis via enhancing the TFEB-mediated autophagy-lysosome pathway in diabetic nephropathy

Y Wang, L Peng, X Lu, H Zhang, H Zhao, T Zhao… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Diabetic nephropathy (DN) is the leading cause of end-
stage kidney disease and currently there are no specific and effective drugs for its treatment …

Autophagy3D: a comprehensive autophagy structure database

Neha, J Castin, S Fatihi, D Gahlot, A Arun, L Thukral - Database, 2024 - academic.oup.com
Autophagy pathway plays a central role in cellular degradation. The proteins involved in the
core autophagy process are mostly localised on membranes or interact indirectly with lipid …

Oscillatory autophagy induction is enabled by an updated AMPK-ULK1 regulatory wiring

O Kapuy, M Holczer, L Csabai, T Korcsmáros - PloS one, 2024 - journals.plos.org
Autophagy-dependent survival relies on a crucial oscillatory response during cellular stress.
Although oscillatory behaviour is typically associated with processes like the cell cycle or …