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Targeting microRNAs in cancer: rationale, strategies and challenges
MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs that regulate
gene expression. Early studies have shown that miRNA expression is deregulated in cancer …
gene expression. Early studies have shown that miRNA expression is deregulated in cancer …
The pervasive role of the miR-181 family in development, neurodegeneration, and cancer
MicroRNAs (miRNAs) are small noncoding RNAs playing a fundamental role in the
regulation of gene expression. Evidence accumulating in the past decades indicate that they …
regulation of gene expression. Evidence accumulating in the past decades indicate that they …
Detection of microRNA expression in human peripheral blood microvesicles
Background MicroRNAs (miRNA) are small non-coding RNAs that regulate translation of
mRNA and protein. Loss or enhanced expression of miRNAs is associated with several …
mRNA and protein. Loss or enhanced expression of miRNAs is associated with several …
Selective release of microRNA species from normal and malignant mammary epithelial cells
L Pigati, SCS Yaddanapudi, R Iyengar, DJ Kim… - PloS one, 2010 - journals.plos.org
MicroRNAs (miRNAs) in body fluids are candidate diagnostics for a variety of conditions and
diseases, including breast cancer. One premise for using extracellular miRNAs to diagnose …
diseases, including breast cancer. One premise for using extracellular miRNAs to diagnose …
MicroRNAs: new regulators of immune cell development and function
Decades of research went into understanding immune cell development and function
without awareness that consideration of a key element, microRNA (miRNA), was lacking …
without awareness that consideration of a key element, microRNA (miRNA), was lacking …
OncomiRs: the discovery and progress of microRNAs in cancers
WCS Cho - Molecular cancer, 2007 - Springer
Abstract microRNAs (miRNAs) are evolutionarily conserved, endogenous, small, noncoding
RNA molecules of about 22 nucleotides in length that function as posttranscriptional gene …
RNA molecules of about 22 nucleotides in length that function as posttranscriptional gene …
MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis
F Pichiorri, SS Suh, M Ladetto, M Kuehl… - Proceedings of the …, 2008 - pnas.org
Progress in understanding the biology of multiple myeloma (MM), a plasma cell malignancy,
has been slow. The discovery of microRNAs (miRNAs), a class of small noncoding RNAs …
has been slow. The discovery of microRNAs (miRNAs), a class of small noncoding RNAs …
[HTML][HTML] Inflammation and nutritional science for programs/policies and interpretation of research evidence (INSPIRE)
An increasing recognition has emerged of the complexities of the global health agenda—
specifically, the collision of infections and noncommunicable diseases and the dual burden …
specifically, the collision of infections and noncommunicable diseases and the dual burden …
Cancer chemoprevention by natural products: how far have we come?
Since ancient times, natural products, herbs and spices have been used for preventing
several diseases, including cancer. The term chemoprevention was coined in the late 1970s …
several diseases, including cancer. The term chemoprevention was coined in the late 1970s …
Distinct microRNA expression profiles in acute myeloid leukemia with common translocations
Z Li, J Lu, M Sun, S Mi, H Zhang, RT Luo… - Proceedings of the …, 2008 - pnas.org
MicroRNAs (miRNAs) are postulated to be important regulators in cancers. Here, we report a
genome-wide miRNA expression analysis in 52 acute myeloid leukemia (AML) samples with …
genome-wide miRNA expression analysis in 52 acute myeloid leukemia (AML) samples with …