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Antibacterial strategies inspired by the oxidative stress and response networks
Oxidative stress arises from an imbalance between the excessive accumulation of reactive
oxygen species (ROS) and a cell's capability to readily detoxify them. Although ROS are …
oxygen species (ROS) and a cell's capability to readily detoxify them. Although ROS are …
Journey on naphthoquinone and anthraquinone derivatives: new insights in Alzheimer's disease
M Campora, V Francesconi, S Schenone, B Tasso… - Pharmaceuticals, 2021 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease that is characterized
by memory loss, cognitive impairment, and functional decline leading to dementia and …
by memory loss, cognitive impairment, and functional decline leading to dementia and …
Noteworthy secondary metabolites naphthoquinones-their occurrence, pharmacological properties and analysis
P Babula, V Adam, L Havel… - Current Pharmaceutical …, 2009 - benthamdirect.com
Chemical investigation of many bacterial and fungal, as well as plant species has revealed
the presence of interesting compounds derived from naphthalene-1, 4-naphthoquinones …
the presence of interesting compounds derived from naphthalene-1, 4-naphthoquinones …
Juglone, a naphthoquinone from walnut, exerts cytotoxic and genotoxic effects against cultured melanoma tumor cells
This study demonstrates cytotoxic and genotoxic potential of juglone, a chief constituent of
walnut, and its underlying mechanisms against melanoma cells. MTT assay and clonogenic …
walnut, and its underlying mechanisms against melanoma cells. MTT assay and clonogenic …
Nonenzymatic reduction of thymoquinone in physiological conditions
Thymoquinone (TQ) is the bioactive constituent of the volatile oil of Nigella sativa L. and has
been shown to exert antioxidant antineoplastic and anti-inflammatory effects. During the …
been shown to exert antioxidant antineoplastic and anti-inflammatory effects. During the …
Activity guided isolation and modification of juglone from Juglans regia as potent cytotoxic agent against lung cancer cell lines
XB Zhang, CL Zou, YX Duan, F Wu, G Li - BMC Complementary and …, 2015 - Springer
Background Juglans regia has been found to exhibit significant anticancer activity against
various human cancer cell lines. This study was undertaken to isolate the active chemical …
various human cancer cell lines. This study was undertaken to isolate the active chemical …
Pro-oxidants ameliorate radiation-induced apoptosis through activation of the calcium–ERK1/2–Nrf2 pathway
There are no reports describing the ability of pro-oxidants to protect against radiation-
induced apoptosis. Activation of the redox-sensitive transcription factor Nrf2 by low levels of …
induced apoptosis. Activation of the redox-sensitive transcription factor Nrf2 by low levels of …
Synthesis and cytotoxic activity of metallic complexes of lawsone
S Oramas-Royo, C Torrejon, I Cuadrado… - Bioorganic & Medicinal …, 2013 - Elsevier
In the present study, a series of metallic complexes of the 1, 4-naphthoquinone lawsone (2–
6) were synthesized and evaluated for potential cytotoxicity in a mouse leukemic …
6) were synthesized and evaluated for potential cytotoxicity in a mouse leukemic …
[HTML][HTML] Synthesis of New 1, 4-Naphthoquinone Fluorosulfate Derivatives and the Study of Their Biological and Electrochemical Properties
This study presents the synthesis of new fluorosulfate derivatives of 1, 4-naphthoquinone by
the SuFEx reaction. Anticancer properties of obtained compounds were studied on PC-3 …
the SuFEx reaction. Anticancer properties of obtained compounds were studied on PC-3 …
Benzylpyrazolyl naphthoquinones as potential VEGFR-2, GPCR and PPAR inhibitors: Synthesis, anti-cancer evaluation, molecular docking and DFT studies
The present study reports the synthesis of benzylpyrazolyl naphthoquinones using nano-Fe
3 O 4 supported Bronsted acidic ionic liquid ([nano-Fe 3 O 4@ BenzImi] SO 3 H) as …
3 O 4 supported Bronsted acidic ionic liquid ([nano-Fe 3 O 4@ BenzImi] SO 3 H) as …