The rapid growth of biotherapeutic industry, with more and more complex molecules
entering the market, forces the need for advanced analytical platforms that can quickly and …

The multi-attribute method (MAM) is a liquid chromatography-mass spectrometry (LC-MS)-
based method that is used to directly characterize and monitor numerous product quality …

Biopharmaceuticals are one of the fastest-growing sectors in the biotechnology industry.
Within the umbrella of biopharmaceuticals, the biosimilar segment is expanding with …

The multi-attribute method (MAM), a liquid chromatography-mass spectrometry (LC-MS)-
based peptide map** method, has gained increased interest and applications in the …

Structures for lossless ion manipulation-based high-resolution ion mobility (HRIM) interfaced
with mass spectrometry has emerged as a powerful tool for the separation and analysis of …

The availability of rapid methods that can accurately define and quantify biopharmaceutical
critical quality attributes has been the driving force for the implementation of mass …

In the quest to market increasingly safer and more potent biotherapeutic proteins, the
concept of the multi-attribute method (MAM) has emerged from biopharmaceutical …

Post-translational modifications (PTMs) that impact the safety or efficacy of protein
therapeutics are critical quality attributes (CQAs) that need to be controlled to ensure product …

New peak detection (NPD), as part of the LC–MS-based multi-attribute method (MAM),
allows for sensitive and unbiased detection of new or changing site-specific attributes …

With growing maturity of the biopharmaceutical industry, new modalities entering the
therapeutic design space and increasing complexity of formulations such as combination …