Hippocampal dysfunction in the pathophysiology of schizophrenia: a selective review and hypothesis for early detection and intervention
Scientists have long sought to characterize the pathophysiologic basis of schizophrenia and
develop biomarkers that could identify the illness. Extensive postmortem and in vivo …
develop biomarkers that could identify the illness. Extensive postmortem and in vivo …
A survey of methods for 3D histology reconstruction
Histology permits the observation of otherwise invisible structures of the internal topography
of a specimen. Although it enables the investigation of tissues at a cellular level, it is invasive …
of a specimen. Although it enables the investigation of tissues at a cellular level, it is invasive …
Adolescence is associated with genomically patterned consolidation of the hubs of the human brain connectome
How does human brain structure mature during adolescence? We used MRI to measure
cortical thickness and intracortical myelination in 297 population volunteers aged 14–24 y …
cortical thickness and intracortical myelination in 297 population volunteers aged 14–24 y …
Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism
C Monteiro, L Miarka, M Perea-García, N Priego… - Nature medicine, 2022 - nature.com
Whole-brain radiotherapy (WBRT) is the treatment backbone for many patients with brain
metastasis; however, its efficacy in preventing disease progression and the associated …
metastasis; however, its efficacy in preventing disease progression and the associated …
Adolescent tuning of association cortex in human structural brain networks
Motivated by prior data on local cortical shrinkage and intracortical myelination, we
predicted age-related changes in topological organization of cortical structural networks …
predicted age-related changes in topological organization of cortical structural networks …
Small extracellular vesicles from young plasma reverse age-related functional declines by improving mitochondrial energy metabolism
X Chen, Y Luo, Q Zhu, J Zhang, H Huang, Y Kan, D Li… - Nature Aging, 2024 - nature.com
Recent investigations into heterochronic parabiosis have unveiled robust rejuvenating
effects of young blood on aged tissues. However, the specific rejuvenating mechanisms …
effects of young blood on aged tissues. However, the specific rejuvenating mechanisms …
Developmental mouse brain common coordinate framework
Abstract 3D brain atlases are key resources to understand the brain's spatial organization
and promote interoperability across different studies. However, unlike the adult mouse brain …
and promote interoperability across different studies. However, unlike the adult mouse brain …
Microbiota influence the development of the brain and behaviors in C57BL/6J mice
We investigated the contributions of commensal bacteria to brain structural maturation by
magnetic resonance imaging and behavioral tests in four and 12 weeks old C57BL/6J …
magnetic resonance imaging and behavioral tests in four and 12 weeks old C57BL/6J …
Resveratrol, metabolic dysregulation, and Alzheimer's disease: Considerations for neurogenerative disease
AJT Yang, A Bagit, REK MacPherson - International Journal of Molecular …, 2021 - mdpi.com
Alzheimer's disease (AD) has traditionally been discussed as a disease where serious
cognitive decline is a result of A β-plaque accumulation, tau tangle formation, and …
cognitive decline is a result of A β-plaque accumulation, tau tangle formation, and …
Comparative modeling of transcranial magnetic and electric stimulation in mouse, monkey, and human
Transcranial magnetic stimulation (TMS) and transcranial electric stimulation (TES) are
increasingly popular methods to noninvasively affect brain activity. However, their …
increasingly popular methods to noninvasively affect brain activity. However, their …