Proposing novel natural compounds against Alzheimer's disease targeting acetylcholinesterase
Alzheimer's disease (AD) is a neurodegenerative disorder considered as a global public
health threat influencing many people. Despite the concerning rise in the affected …
health threat influencing many people. Despite the concerning rise in the affected …
Medicinal Plants-A Promising Breakthrough in the Management of Alzheimer's Disease Progression Compared to NSAID: A Systematic Review
Treatment of Alzheimer's Disease is currently limited only to slowing the progression of the
symptoms, not curing the disease. Current FDA-approved therapies such as Donepezil …
symptoms, not curing the disease. Current FDA-approved therapies such as Donepezil …
An In-silico Approach: Design, Homology Modeling, Molecular Docking, MM/GBSA Simulations, and ADMET Screening of Novel 1,3,4-oxadiazoles as PLK1inhibitors
S Malkaje, MG Srinivasa… - … : Current Drug Abuse …, 2023 - benthamdirect.com
Background: Breast cancer is the most commonly diagnosed and major cause of cancer-
related deaths in women worldwide. Disruption of the normal regulation of cell cycle …
related deaths in women worldwide. Disruption of the normal regulation of cell cycle …
Structure‐based design of new N‐benzyl‐piperidine derivatives as multitarget‐directed AChE/BuChE inhibitors for Alzheimer's disease
RA Conceição, N von Ranke, L Azevedo… - Journal of Cellular …, 2023 - Wiley Online Library
The pathogenic complexity of Alzheimer's disease (AD) demands the development of
multitarget‐directed agents aiming at improving actual pharmacotherapy. Based on the …
multitarget‐directed agents aiming at improving actual pharmacotherapy. Based on the …
Revealing the Acetylcholinesterase Inhibitory Potential of Phyllanthus amarus and Its Phytoconstituents: In Vitro and in Silico Approach
KO Faloye, S Mahmud, EG Fakola… - … and biology insights, 2022 - journals.sagepub.com
The inhibition of acetylcholinesterase plays a vital role in the treatment of Alzheimer disease.
This study aimed to explore the acetylcholinesterase inhibition potential of Phyllanthus …
This study aimed to explore the acetylcholinesterase inhibition potential of Phyllanthus …
Computational identification of potential acetylcholinesterase (AChE) and monoamine oxidase-B inhibitors from Vitis vinifera: a case study of Alzheimer's disease (AD …
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease that affects
people aged 60 years and above. Yet, the discovery of potent therapeutic agents against …
people aged 60 years and above. Yet, the discovery of potent therapeutic agents against …
Sappanin-type homoisoflavonoids from Scilla nervosa inhibits acetylcholinesterase enzyme: a combined in silico and in vitro approach
Alzheimer's disease is among the major health challenges that currently attract the attention
of health care givers and drug discovery and development experts worldwide. This study …
of health care givers and drug discovery and development experts worldwide. This study …
An In-silico Approach to Identify Potential Drug Molecules for Alzheimer's Disease: A Case Involving Four Therapeutic Targets
Background: Computational methods in the 'omics' era have proved to be a boon in the drug
discovery field. Bioinformatics and cheminformatics databases and tools complement the …
discovery field. Bioinformatics and cheminformatics databases and tools complement the …
Computational screening of phytochemicals for anti-parasitic drug discovery
In silico techniques reduce the need for rigorous animal experimentations. It is time-efficient,
eco-friendly, sustainable, and also adheres to the principle of green chemistry. In silico …
eco-friendly, sustainable, and also adheres to the principle of green chemistry. In silico …
[PDF][PDF] Traditional medicines and experimental analysis methods for Alzheimer's disease
HZ Kombo, S Kumar, G Singh - Tradit Med Res, 2022 - researchgate.net
Alzheimer's disease is a complex neurodegenerative ailment accompanied by cognitive
problems and progressive memory loss. The main causes of the disease are …
problems and progressive memory loss. The main causes of the disease are …