Macrophage polarization in response to epigenetic modifiers during infection and inflammation

U Patel, S Rajasingh, S Samanta, T Cao, B Dawn… - Drug discovery today, 2017 - Elsevier
Highlights•This review is focusing on polarization of macrophages by epigenetic
modifications.•M1/M2 macrophages are flawlessly synchronized, specialized, and perform …

Caspase-11, a specific sensor for intracellular lipopolysaccharide recognition, mediates the non-canonical inflammatory pathway of pyroptosis

X Huang, Y Feng, G **ong, S Whyte, J Duan, Y Yang… - Cell & bioscience, 2019 - Springer
Pyroptosis, a type of programmed cell death that along with inflammation, is mainly
regulated by two main pathways, cysteinyl aspartate specific proteinase (caspase)-1 …

Synthesis and antiviral activity of a new coumarin derivative against spring viraemia of carp virus

YF Shen, L Liu, CZ Feng, Y Hu, C Chen… - Fish & shellfish …, 2018 - Elsevier
Coumarin as a lead structure have received a considerable attention in the last three
decades for the discovery of antiviral agents. Our previous study indicated that imidazole …

[HTML][HTML] Potential aquatic environmental risks of trifloxystrobin: Enhancement of virus susceptibility in zebrafish through initiation of autophagy

H Wang, TX Qiu, JF Lu, HW Liu, L Hu, L Liu… - Zoological …, 2021 - ncbi.nlm.nih.gov
Chronic pollution in aquatic ecosystems can lead to many adverse effects, including a
greater susceptibility to pathogens among resident biota. Trifloxystrobin (TFS) is a strobilurin …

Inflammasomes in teleosts: structures and mechanisms that induce pyroptosis during bacterial infection

N Morimoto, T Kono, M Sakai, J Hikima - International journal of molecular …, 2021 - mdpi.com
Pattern recognition receptors (PRRs) play a crucial role in inducing inflammatory responses;
they recognize pathogen-associated molecular patterns, damage-associated molecular …

Zebrafish as a model for fish diseases in aquaculture

LG Jørgensen - Pathogens, 2020 - mdpi.com
The use of zebrafish as a model for human conditions is widely recognized. Within the last
couple of decades, the zebrafish has furthermore increasingly been utilized as a model for …

An imidazole coumarin derivative enhances the antiviral response to spring viremia of carp virus infection in zebrafish

L Liu, Y Hu, J Lu, G Wang - Virus research, 2019 - Elsevier
As an efficient pathogen resulting in economic impact in aquaculture, spring viremia of carp
virus (SVCV) causes devastating disease in cyprinids. Based on the previous study that 7-(6 …

Modelling viral infections using zebrafish: innate immune response and antiviral research

M Varela, A Figueras, B Novoa - Antiviral research, 2017 - Elsevier
Zebrafish possess a highly developed immune system that is remarkably similar to the
human one. Therefore, it is expected that the majority of the signalling pathways and …

Cell death as part of innate immunity: Cause or consequence?

M Riera Romo - Immunology, 2021 - Wiley Online Library
Regulated or programmed cell death plays a critical role in the development and tissue
organization and function. In addition, it is intrinsically connected with immunity and host …

Molecular actors of inflammation and their signaling pathways: mechanistic insights from zebrafish

J Leiba, R Özbilgiç, L Hernández, M Demou, G Lutfalla… - Biology, 2023 - mdpi.com
Simple Summary Inflammation is a central part of the body's response to harm that can be
elicited by microbes, environmental factors, or internal injuries. This complex physiological …