Simple Summary Copper supplementation in ruminants deserves special attention because
of the narrow margin between deficiency and toxicity, both of which ruminants are …

Hepatic fibrosis is commonly diagnosed in dogs, often as a sequela to chronic hepatitis
(CH). The development of fibrosis is a crucial event in the progression of hepatic disease …

This consensus statement on chronic hepatitis (CH) in dogs is based on the expert opinion
of 7 specialists with extensive experience in diagnosing, treating, and conducting clinical …

ABSTRACT A 7 yr old castrated male Cavalier King Charles spaniel presented for
evaluation of liver enzyme elevations. Abdominal ultrasound revealed a small liver with …

The objective of this study was to evaluate the macronutrients composition, fatty acid and
amino acid profiles, and essential minerals content of all vegan foods for dogs and cats …

Renal fibrosis relies on multiple proteins and cofactors in its gradual development. Copper is
a cofactor of many enzymes involved in renal microenvironment homeostasis. We previously …

Copper is a trace element essential for numerous biological activities, whereas the
mitochondria serve as both major sites of intracellular copper utilization and copper …

Background Copper associated hepatitis (CAH) has been increasingly recognized in dogs,
and speculation exists that hereditary defects in copper metabolism have been exacerbated …

Objectives The aim of this study was to assess laser ablation-inductively coupled plasma-
mass spectrometry (LA-ICP-MS) as a tool for measuring concentrations and determining …

Background Hepatocellular carcinoma (HCC) is the most common primary liver tumor in
dogs. Abnormalities in hepatic copper, iron, zinc, and selenium concentrations increase risk …