Aptamers are RNA/DNA oligonucleotide molecules that specifically bind to a targeted
complementary molecule. As potential recognition elements with promising diagnostic and …

Aptamers are single-stranded DNA or RNA sequences that bind target molecules with high
specificity and affinity. Aptamers exhibit several notable advantages over protein-based …

Glycosylation is highly prevalent, and also one of the most complex and varied
posttranslational modifications. This large glycan diversity results in a wide range of …

During infection neuraminidase desialylates platelets and induces their rapid clearance from
circulation. The underlying molecular basis, particularly the role of platelet glycoprotein (GP) …

Introduction Aptamers provide exciting opportunities for the development of specific and
targeted therapeutic approaches. Areas covered In this review, the authors discuss different …

Platelet transfusion, both prophylactic and therapeutic, is a key element in modern medicine.
Currently, the standard platelet product for clinical use is platelet concentrates at room …

Although procoagulant TF is clearly expressed in the vascular subendothelium, it has also
been proposed that many different cell types express an inactive, encrypted form of TF that …

Aptamers have shown potential for diagnosing clinical markers and targeted treatment of
diseases. However, their limited stability and short half-life hinder their broader applications …

Patients with thrombocytopenia require platelet transfusion to prevent and stop hemorrhage.
Cold storage of platelets results in complex molecular lesions, including changes in …

Platelets play vital roles in vascular repair, especially in primary hemostasis, and have been
widely used in transfusion to prevent bleeding or manage active bleeding. Recently …