Next-generation insect-resistant plants: RNAi-mediated crop protection

J Zhang, SA Khan, DG Heckel, R Bock - Trends in biotechnology, 2017 - cell.com
Plant-mediated RNA interference (RNAi) shows great potential in crop protection. It relies on
plants stably expressing double-stranded RNAs (dsRNAs) that target essential genes in pest …

Towards the elements of successful insect RNAi

JG Scott, K Michel, LC Bartholomay… - Journal of insect …, 2013 - Elsevier
RNA interference (RNAi), the sequence-specific suppression of gene expression, offers
great opportunities for insect science, especially to analyze gene function, manage pest …

RNA interference in insects: protecting beneficials and controlling pests

E Vogel, D Santos, L Mingels, TW Verdonckt… - Frontiers in …, 2019 - frontiersin.org
Insects constitute the largest and most diverse group of animals on Earth with an equally
diverse virome. The main antiviral immune system of these animals is the post …

Increased RNAi Efficacy in Spodoptera exigua via the Formulation of dsRNA With Guanylated Polymers

O Christiaens, MG Tardajos, ZL Martinez Reyna… - Frontiers in …, 2018 - frontiersin.org
Lepidoptera comprise some of the most devastating herbivorous pest insects worldwide.
One of the most promising novel pest control strategies is exploiting the RNA interference …

Comparative analysis of double-stranded RNA degradation and processing in insects

IK Singh, S Singh, K Mogilicherla, JN Shukla… - Scientific reports, 2017 - nature.com
RNA interference (RNAi) based methods are being developed for pest management. A few
products for control of coleopteran pests are expected to be commercialized soon. However …

A nuclease specific to lepidopteran insects suppresses RNAi

RB Guan, HC Li, YJ Fan, SR Hu, O Christiaens… - Journal of Biological …, 2018 - jbc.org
More than 70% of all agricultural pests are insects in the order Lepidoptera, which, unlike
other related insect orders, are not very sensitive to RNAi, limiting genetic studies of this …

DsRNA degradation in the pea aphid (Acyrthosiphon pisum) associated with lack of response in RNAi feeding and injection assay

O Christiaens, L Swevers, G Smagghe - Peptides, 2014 - Elsevier
Over the past decade, RNA interference (RNAi), the sequence-specific suppression of gene
expression, has proven very promising for molecular research in many species, including …

Knockdown of nuclease activity in the gut enhances RNAi efficiency in the Colorado potato beetle, Leptinotarsa decemlineata, but not in the desert locust …

J Spit, A Philips, N Wynant, D Santos… - Insect biochemistry and …, 2017 - Elsevier
The responsiveness towards orally delivered dsRNA and the potency of a subsequent
environmental RNA interference (RNAi) response strongly differs between different insect …

Liposome encapsulation and EDTA formulation of dsRNA targeting essential genes increase oral RNAi‐caused mortality in the Neotropical stink bug Euschistus heros

NL Castellanos, G Smagghe, R Sharma… - Pest Management …, 2019 - Wiley Online Library
BACKGROUND The Neotropical stink bug Euschistus heros is a major pest in soybean
fields. Development of highly species‐specific pesticides based on RNA interference (RNAi) …

Establishing RNAi for basic research and pest control and identification of the most efficient target genes for pest control: a brief guide

S Mehlhorn, VS Hunnekuhl, S Geibel, R Nauen… - Frontiers in …, 2021 - Springer
RNA interference (RNAi) has emerged as a powerful tool for knocking-down gene function
in diverse taxa including arthropods for both basic biological research and application in …