DNA glycosylases in the base excision repair of DNA
HE Krokan, R Standal, G Slupphaug - Biochemical Journal, 1997 - portlandpress.com
A wide range of cytotoxic and mutagenic DNA bases are removed by different DNA
glycosylases, which initiate the base excision repair pathway. DNA glycosylases cleave the …
glycosylases, which initiate the base excision repair pathway. DNA glycosylases cleave the …
A high-coverage Neandertal genome from Vindija Cave in Croatia
To date, the only Neandertal genome that has been sequenced to high quality is from an
individual found in Southern Siberia. We sequenced the genome of a female Neandertal …
individual found in Southern Siberia. We sequenced the genome of a female Neandertal …
Manual and automated preparation of single-stranded DNA libraries for the sequencing of DNA from ancient biological remains and other sources of highly degraded …
MT Gansauge, A Aximu-Petri, S Nagel, M Meyer - Nature Protocols, 2020 - nature.com
It has been shown that highly fragmented DNA is most efficiently converted into DNA
libraries for sequencing if both strands of the DNA fragments are processed independently …
libraries for sequencing if both strands of the DNA fragments are processed independently …
A high-coverage genome sequence from an archaic Denisovan individual
We present a DNA library preparation method that has allowed us to reconstruct a high-
coverage (30×) genome sequence of a Denisovan, an extinct relative of Neandertals. The …
coverage (30×) genome sequence of a Denisovan, an extinct relative of Neandertals. The …
Partial uracil–DNA–glycosylase treatment for screening of ancient DNA
The challenge of sequencing ancient DNA has led to the development of specialized
laboratory protocols that have focused on reducing contamination and maximizing the …
laboratory protocols that have focused on reducing contamination and maximizing the …
Ancient genomic changes associated with domestication of the horse
The genomic changes underlying both early and late stages of horse domestication remain
largely unknown. We examined the genomes of 14 early domestic horses from the Bronze …
largely unknown. We examined the genomes of 14 early domestic horses from the Bronze …
A nucleotide-flip** mechanism from the structure of human uracil–DNA glycosylase bound to DNA
G Slupphaug, CD Mol, B Kavli, AS Arvai, HE Krokan… - Nature, 1996 - nature.com
ANY uracil bases in DNA, a result of either misincorporation or deamination of cytosine, are
removed by uracil-DNA glycosylase (UDG), one of the most efficient and specific of the base …
removed by uracil-DNA glycosylase (UDG), one of the most efficient and specific of the base …
[HTML][HTML] Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA
SS Parikh, CD Mol, G Slupphaug, S Bharati… - The EMBO …, 1998 - embopress.org
Three high-resolution crystal structures of DNA complexes with wild-type and mutant human
uracil-DNA glycosylase (UDG), coupled kinetic characterizations and comparisons with the …
uracil-DNA glycosylase (UDG), coupled kinetic characterizations and comparisons with the …
Comparing the performance of three ancient DNA extraction methods for high‐throughput sequencing
The DNA molecules that can be extracted from archaeological and palaeontological
remains are often degraded and massively contaminated with environmental microbial …
remains are often degraded and massively contaminated with environmental microbial …
Uracil-excision DNA repair
DW Mosbaugh, SE Bennett - Progress in nucleic acid research and …, 1994 - Elsevier
Publisher Summary Uracil residues are introduced into prokaryotic and eukaryotic
deoxyribonucleic acid (DNA) as a normal physiological process during DNA synthesis, and …
deoxyribonucleic acid (DNA) as a normal physiological process during DNA synthesis, and …