Overcoming barriers to patient adherence: the case for develo** innovative drug delivery systems

TH Baryakova, BH Pogostin, R Langer… - Nature Reviews Drug …, 2023 - nature.com
Poor medication adherence is a pervasive issue with considerable health and
socioeconomic consequences. Although the underlying reasons are generally understood …

The promise of improved adherence with long-acting antiretroviral therapy: what are the data?

KK Scarsi, S Swindells - … of Providers of AIDS Care (JIAPAC), 2021 - journals.sagepub.com
As with other chronic conditions, adherence to daily medications remains a challenge for
many individuals living with HIV due to structural, behavioral, and social barriers …

Week 96 extension results of a phase 3 study evaluating long-acting cabotegravir with rilpivirine for HIV-1 treatment

S Swindells, T Lutz, L Van Zyl, N Porteiro, M Stoll… - Aids, 2022 - journals.lww.com
Background: ATLAS (NCT02951052), a phase 3, multicenter, open-label study,
demonstrated that switching to injectable cabotegravir (CAB) with rilpivirine (RPV) long …

Medical mistrust among women with intersecting marginalized identities: a sco** review

IK Ho, TA Sheldon, E Botelho - Ethnicity & Health, 2022 - Taylor & Francis
The purpose of this sco** review is to synthesize knowledge about medical mistrust and
health among women who occupy other marginalized identities; namely women who also …

Patient-reported outcomes through 1 year of an HIV-1 clinical trial evaluating long-acting cabotegravir and rilpivirine administered every 4 or 8 weeks (ATLAS-2M)

V Chounta, ET Overton, A Mills, S Swindells… - The Patient-Patient …, 2021 - Springer
Background Advances in HIV-1 therapeutics have led to the development of a range of daily
oral treatment regimens, which share similar high efficacy rates. Consequently, more …

Perspectives on preparing for long-acting injectable treatment for HIV among consumer, clinical and nonclinical stakeholders: a qualitative study exploring the …

O Jolayemi, LM Bogart, ED Storholm… - PloS one, 2022 - journals.plos.org
Long-acting injectable (LAI) antiretroviral therapy (ART) is a novel HIV treatment option for
people with HIV. The first LAI ART regimen for HIV treatment received regulatory approval in …

Barriers to uptake of long-acting antiretroviral products for treatment and prevention of human immunodeficiency virus (HIV) in high-income countries

SE Cooper, J Rosenblatt… - Clinical Infectious Diseases, 2022 - academic.oup.com
Long-acting injectable antiretroviral therapy (LAI-ART) for the treatment and prevention of
human immunodeficiency virus (HIV) holds great potential to shift treatment paradigms by …

The LAIs are coming! Implementation science considerations for long-acting injectable antiretroviral therapy in the United States: a sco** review

JT Kanazawa, P Saberi, JA Sauceda… - AIDS research and …, 2021 - liebertpub.com
Long-acting injectable antiretroviral therapy (LAI-ART) is one of the latest advancements in
HIV control with the potential to overcome oral ART barriers to adherence. The objective of …

A qualitative exploration of women's interest in long-acting injectable antiretroviral therapy across six cities in the women's interagency HIV study: intersections with …

MM Philbin, C Parish, S Bergen, D Kerrigan… - AIDS patient care and …, 2021 - liebertpub.com
Medications for antiretroviral therapy (ART) and preexposure prophylaxis (PrEP) are
currently daily pill regimens, which pose barriers to long-term adherence. Long-acting …

Impact of long-acting therapies on the global HIV epidemic

NC Chandiwana, CM Serenata, A Owen, S Rannard… - Aids, 2021 - journals.lww.com
Long-acting antiretroviral drugs have emerged as exciting treatment and preexposure
prophylaxis (PrEP) options for people with HIV and at risk of HIV. Long-acting regimens may …