Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

Myxococcus xanthus, like other myxobacteria, is a social bacterium that moves and feeds
cooperatively in predatory groups. On surfaces, rod-shaped vegetative cells move in search …

Genome mining has become a key technology to exploit natural product diversity. Although
initially performed on a single-genome basis, the process is now being scaled up to mine …

Although biosynthetic gene clusters (BGCs) have been discovered for hundreds of bacterial
metabolites, our knowledge of their diversity remains limited. Here, we used a novel …

Background Recovering individual genomes from metagenomic datasets allows access to
uncultivated microbial populations that may have important roles in natural and engineered …

Cultivated bacteria such as actinomycetes are a highly useful source of biomedically
important natural products. However, such 'talented'producers represent only a minute …

Research on how bacteria adapt to changing environments underlies the contemporary
biological understanding of signal transduction (ST), and ST provides the foundation of the …

Background One of the main challenges in metagenomics is the identification of
microorganisms in clinical and environmental samples. While an extensive and …

Actinomycetes are historically important sources for secondary metabolites (SMs) with
applications in human medicine, animal health, and plant crop protection. It is now clear that …

Calcium (Ca) can contribute to soil organic carbon (SOC) persistence by mediating physico-
chemical interactions between organic compounds and minerals. Yet, Ca is also crucial for …