Atomically dispersed Co-N/C catalyst for divergent synthesis of nitrogen-containing compounds from alkenes

W Xue, Z Zhu, S Chen, B You… - Journal of the American …, 2023 - ACS Publications
Alkene functionalization with a single-atom catalyst (SAC) which merges homogeneous and
heterogeneous catalysis is a fascinating route to obtain high-value-added molecules …

Homogeneous Iron Catalyzed C− H Amination

D Possenti, G Olivo - ChemCatChem, 2024 - Wiley Online Library
Iron‐catalyzed C− H amination is emerging as an attractive and sustainable method to
install amine functionalities into organic compounds. Amination of C (sp3)− H bonds is …

Enzymatic nitrogen incorporation using hydroxylamine

S Gao, A Das, E Alfonzo, KM Sicinski… - Journal of the …, 2023 - ACS Publications
Hydroxylamine-derived reagents have enabled versatile nitrene transfer reactions for
introducing nitrogen-containing functionalities in small-molecule catalysis, as well as …

Reaction Discovery Using Spectroscopic Insights from an Enzymatic C–H Amination Intermediate

A Das, S Gao, RG Lal, MH Hicks… - Journal of the …, 2024 - ACS Publications
Engineered hemoproteins can selectively incorporate nitrogen from nitrene precursors like
hydroxylamine, O-substituted hydroxylamines, and organic azides into organic molecules …

Difunctionalization Processes Enabled by Hexafluoroisopropanol

M Piejko, J Moran, D Lebœuf - ACS Organic & Inorganic Au, 2024 - ACS Publications
In the past 5 years, hexafluoroisopropanol (HFIP) has been used as a unique solvent or
additive to enable challenging transformations through substrate activation and stabilization …

Harnessing bromo/acyloxy transposition (BrAcT) and excited-state copper catalysis for styrene difunctionalization

U Mukherjee, JA Shah, DG Musaev… - Journal of the American …, 2024 - ACS Publications
1, 2-Difunctionalization of styrenes, adding two distinct functional groups across the C═ C
double bond, has emerged as a powerful tool for enhancing molecular complexity. Herein …

Synthesis of Unprotected β‐Arylethylamines by Iron (II)‐Catalyzed 1, 2‐Aminoarylation of Alkenes in Hexafluoroisopropanol

V Pozhydaiev, M Vayer, C Fave, J Moran… - Angewandte …, 2023 - Wiley Online Library
Abstract β‐Arylethylamines are prevalent structural motifs in molecules exhibiting biological
activity. Here we report a sequential one‐pot protocol for the 1, 2‐aminoarylation of alkenes …

Direct C− C Double Bond Cleavage of Alkenes Enabled by Highly Dispersed Cobalt Catalyst and Hydroxylamine

W Xue, Y Jiang, H Lu, B You, X Wang… - Angewandte …, 2023 - Wiley Online Library
The utilization of a single‐atom catalyst to break C− C bonds merges the merits of
homogeneous and heterogeneous catalysis and presents an intriguing pathway for …

Ortho-Selective amination of arene carboxylic acids via rearrangement of acyl O-hydroxylamines

JE Gillespie, NYS Lam, RJ Phipps - Chemical Science, 2023 - pubs.rsc.org
Direct amination of arene C–H bonds is an attractive disconnection to form aniline-derived
building blocks. This transformation presents significant practical challenges; classical …

Advancing critical chemical processes for a sustainable future: challenges for industry and the Max Planck–Cardiff centre on the fundamentals of heterogeneous …

M Bowker, S DeBeer, NF Dummer… - Angewandte …, 2022 - Wiley Online Library
Catalysis is involved in around 85% of manufacturing industry and contributes an estimated
25% to the global domestic product, with the majority of the processes relying on …