The influence of red blood cell deformability on hematocrit profiles and platelet margination

B Czaja, M Gutierrez, G Závodszky… - PLoS computational …, 2020 - journals.plos.org
The influence of red blood cell (RBC) deformability in whole blood on platelet margination is
investigated using confocal microscopy measurements of flowing human blood and cell …

A few upstream bifurcations drive the spatial distribution of red blood cells in model microfluidic networks

A Merlo, M Berg, P Duru, F Risso, Y Davit, S Lorthois - Soft Matter, 2022 - pubs.rsc.org
The physics of blood flow in small vessel networks is dominated by the interactions between
Red Blood Cells (RBCs), plasma and blood vessel walls. The resulting couplings between …

[HTML][HTML] Microfluidics approach to the mechanical properties of red blood cell membrane and their effect on blood rheology

C Trejo-Soto, GR Lázaro, I Pagonabarraga… - Membranes, 2022 - mdpi.com
In this article, we describe the general features of red blood cell membranes and their effect
on blood flow and blood rheology. We first present a basic description of membranes and …

Cell-free layer development and spatial organization of healthy and rigid red blood cells in a microfluidic bifurcation

Y Rashidi, O Aouane, A Darras, T John, J Harting… - Soft Matter, 2023 - pubs.rsc.org
Bifurcations and branches in the microcirculation dramatically affect blood flow as they
determine the spatiotemporal organization of red blood cells (RBCs). Such changes in …

Optimizing pressure-driven pulsatile flows in microfluidic devices

SM Recktenwald, C Wagner, T John - Lab on a Chip, 2021 - pubs.rsc.org
Unsteady and pulsatile flows receive increasing attention due to their potential to enhance
various microscale processes. Further, they possess significant relevance for microfluidic …

Cell-free layer of red blood cells in a constricted microfluidic channel under steady and time-dependent flow conditions

SM Recktenwald, K Graessel, Y Rashidi, JN Steuer… - Physical Review …, 2023 - APS
Constricted blood vessels in the circulatory system can severely impact the spatiotemporal
organization of red blood cells (RBCs) causing various physiological complications. In …

Assessing a heterogeneous model for accounting for endovascular devices in hemodynamic simulations of cerebral aneurysms

A Bérod, F Mut, J Cebral, S Mendez… - International Journal …, 2023 - Wiley Online Library
The heterogeneous model developed by Berod et al [Int J Numer Method Biomed Eng 38,
2021] for representing the hemodynamic effects of endovascular prostheses is applied to a …

Spatiotemporal dynamics of dilute red blood cell suspensions in low-inertia microchannel flow

Q Zhou, J Fidalgo, L Calvi, MO Bernabeu, PR Hoskins… - Biophysical …, 2020 - cell.com
Microfluidic technologies are commonly used for the manipulation of red blood cell (RBC)
suspensions and analyses of flow-mediated biomechanics. To enhance the performance of …

Cross-sectional focusing of red blood cells in a constricted microfluidic channel

A Abay, SM Recktenwald, T John, L Kaestner… - Soft Matter, 2020 - pubs.rsc.org
Constrictions in blood vessels and microfluidic devices can dramatically change the spatial
distribution of passing cells or particles and are commonly used in biomedical cell sorting …

Order–disorder transitions within deformable particle suspensions in planar Poiseuille flow

PC Millett - Journal of Fluid Mechanics, 2024 - cambridge.org
Three-dimensional simulations of the ordering of elastic capsule suspensions within planar
Poiseuille flow channels are reported. The simulations utilize the immersed boundary …