Most nanozymes in development for medical applications only exhibit single‐enzyme‐like
activity, and are thus limited by insufficient catalytic activity and dysfunctionality in complex …

Bioactive or nutraceutical ingredients have been widely used in pursuit of health and well-
being. However, the environmental instability, poor solubility and bioavailability, and …

The topology type and the functionalization of pores play an important role in regulating the
performance of covalent organic frameworks. Herein, we designed and synthesized the …

Achieving effective drug delivery to traverse the blood–brain barrier (BBB) and target tumor
cells remains the greatest challenge for brain tumor therapy. Importantly, the overexpressed …

Dynamic therapy (DT) has emerged as a promising cancer therapy due to its non-invasive
treatment and good spatiotemporal control. However, the efficiency of DT is restricted by …

Tumor recurrence remains the leading cause of treatment failure following surgical resection
of glioblastoma (GBM). M2-like tumor-associated macrophages (TAMs) infiltrating the tumor …

Background Ferritin, a ubiquitously distributed iron storage protein, can specifically target
tumor cells through transferrin receptor 1. Due to its rearrangeable nanocage structure …

RNA-based therapeutics have emerged as promising approaches to modulate gene
expression and generate therapeutic proteins or antigens capable of inducing immune …

Herein, we designed Comp. 1 to simultaneously respond to two enzymes: alkaline
phosphatase and matrix metalloproteinase 2, which is commonly found in highly malignant …

Ferritin, a naturally occurring iron storage protein, has gained significant attention as a drug
delivery platform due to its inherent biocompatibility and capacity to encapsulate therapeutic …