DOHaD: a menagerie of adaptations and perspectives: large animal models of developmental programming: sustenance, stress, and sex matter
In brief Developmental programming refers to the long-term programming of gene
expression during fetal and postnatal development, resulting in altered organ function even …
expression during fetal and postnatal development, resulting in altered organ function even …
Role of the placenta in developmental programming: Observations from models using large animals
Developmental programming, which proposes that “insults” or “stressors” during intrauterine
or postnatal development can have not only immediate but also long-term consequences for …
or postnatal development can have not only immediate but also long-term consequences for …
Provision of choline chloride to the bovine preimplantation embryo alters postnatal body size and DNA methylation
MKLJ Haimon, E Estrada-Cortés… - Biology of …, 2024 - academic.oup.com
Choline is a vital micronutrient. In this study, we aimed to confirm, and expand on previous
findings, how choline impacts embryos from the first 7 days of development to affect …
findings, how choline impacts embryos from the first 7 days of development to affect …
Paternal dietary macronutrient balance and energy intake drive metabolic and behavioral differences among offspring
Paternal diet can influence the phenotype of the next generation, yet, the dietary
components inducing specific responses in the offspring are not identified. Here, we use the …
components inducing specific responses in the offspring are not identified. Here, we use the …
Paternal effects on fetal programming
Paternal programming is the concept that the environmental signals from the sire's
experiences leading up to mating can alter semen and ultimately affect the phenotype of …
experiences leading up to mating can alter semen and ultimately affect the phenotype of …
Transgenerational effects of paternal exposures: the role of germline de novo mutations
Germline de novo mutations (DNMs) refer to spontaneous mutations arising during
gametogenesis, resulting in genetic changes within germ cells that are subsequently …
gametogenesis, resulting in genetic changes within germ cells that are subsequently …
C Casciaro, H Hamada, E Bloise… - Trends in Endocrinology & …, 2024 - cell.com
Paternal health and exposure to adverse environments in the period prior to conception
have a profound impact on future generations. Adversities such as stress, diet, and toxicants …
have a profound impact on future generations. Adversities such as stress, diet, and toxicants …