Cellular agriculture for milk bioactive production

L Yart, AW Wijaya, MJ Lima, C Haller… - Nature Reviews …, 2023 - nature.com
Cellular agriculture, that is, the cell culture-based production of food, may provide an
alternative to traditional farming, minimizing the environmental effect, while ensuring …

[HTML][HTML] Advances and applications of capillary electromigration methods in the analysis of therapeutic and diagnostic recombinant proteins–A Review

H Stutz - Journal of Pharmaceutical and Biomedical Analysis, 2023 - Elsevier
This review provides a comprehensive overview of methodological advances and
applications of CE in the analysis and characterization of recombinant therapeutic and …

Overview on the hydrodynamic conditions found in industrial systems and its impact in (bio) fouling formation

S Fernandes, IB Gomes, LC Simões… - Chemical Engineering …, 2021 - Elsevier
Biofouling is the unwanted accumulation of deposits on surfaces, composed by organic and
inorganic particles and (micro) organisms. Its occurrence in industrial equipment is …

Scale-up study of aerated coaxial mixing reactors containing non-newtonian power-law fluids: Analysis of gas holdup, cavity size, and power consumption

A Rahimzadeh, F Ein-Mozaffari, A Lohi - Journal of Industrial and …, 2022 - Elsevier
The use of coaxial mixers has significantly improved gas dispersion in non-Newtonian fluids.
However, to the best of our knowledge, no scale-up investigation of an aerated coaxial mixer …

Fluid dynamic conditions and oxygen availability effects on microbial cultures in STBR: An overview

F Garcia-Ochoa, E Gomez, VE Santos - Biochemical Engineering Journal, 2020 - Elsevier
Bioprocesses are often carried out in stirred tank bioreactors. Due to the need of mixing,
homogenization and interphase transports, cultures are usually agitated by mechanical …

[HTML][HTML] Automated shape and process parameter optimization for scaling up geometrically non-similar bioreactors

S Seidel, F Mozaffari, RW Maschke, M Kraume… - Processes, 2023 - mdpi.com
Scaling bioprocesses remains a major challenge. Since it is physically impossible to
increase all process parameters equally, a suitable scale-up strategy must be selected for a …

Understanding the scale-up of fermentation processes from the viewpoint of the flow field in bioreactors and the physiological response of strains

J **a, G Wang, M Fan, M Chen, Z Wang… - Chinese Journal of …, 2021 - Elsevier
The production capability of a fermentation process is predominately determined by
individual strains, which ultimately affected ultimately by interactions between the scale …

Quantifying the hydrodynamic stress for bioprocesses

U Kaya, S Gopireddy, N Urbanetz… - Biotechnology …, 2023 - Wiley Online Library
Hydrodynamic stress is an influential physical parameter for various bioprocesses, affecting
the performance and viability of the living organisms. However, different approaches are in …

Preclinical research of stem cells: challenges and progress

J Li, Y Wu, X Yao, Y Tian, X Sun, Z Liu, X Ye… - Stem Cell Reviews and …, 2023 - Springer
In recent years, great breakthroughs have been made in basic research and clinical
applications of stem cells in regenerative medicine and other fields, which continue to …

Effect of impeller type and scale-up on spatial distribution of shear rate in a stirred tank

H Wang, X Duan, X Feng, ZS Mao, C Yang - Chinese Journal of Chemical …, 2022 - Elsevier
The main spatial distribution features of shear rate in a stirred tank operated with five
different radial and axial flow impellers were presented with particle image velocimetry (PIV) …