Neurological and psychiatric diseases have high degrees of genetic and pathophysiological
heterogeneity, irrespective of clinical manifestations. Traditional medical paradigms have …

Alzheimer's disease (AD) is the most common form of dementia worldwide, with a complex,
poorly understood pathogenesis. Cerebral atrophy, amyloid-β (Aβ) plaques, and …

The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …

Hemorrhagic stroke is the deadliest form of stroke and includes the subtypes of intracerebral
hemorrhage and subarachnoid hemorrhage. A common cause of hemorrhagic stroke in …

This decade has seen the beginning of ground-breaking conceptual shifts in the research of
Alzheimer's disease (AD), which acknowledges risk elements and the evolving wide …

The blood-brain barrier (BBB) is a selective barrier and a functional gatekeeper for the
central nervous system (CNS), essential for maintaining brain homeostasis. The BBB is …

The integration of artificial intelligence in precision medicine has revolutionized healthcare
delivery. Precision medicine identifies the phenotype of particular patients with less-common …

Targeting neuroinflammation via CD33 inhibition and/or TREM2 activation may have
important implications for neurodegeneration in Alzheimer's disease and may be an addition …

Dementia is a neurodegenerative condition that is considered a major factor contributing to
cognitive decline that reduces independent function. Pathophysiological pathways are not …

Alzheimer's disease is one of the most common age-related neurodegenerative disorders.
The main theory of Alzheimer's disease progress is the amyloid-β cascade hypothesis …