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Fighting bacterial persistence: current and emerging anti-persister strategies and therapeutics
In addition to the well-known strategies of antibiotic resistance and biofilm formation,
bacterial populations possess an additional survival strategy to endure hostile environments …
bacterial populations possess an additional survival strategy to endure hostile environments …
Combination strategies to enhance the efficacy of antimicrobial peptides against bacterial biofilms
The great clinical significance of biofilm-associated infections and their inherent
recalcitrance to antibiotic treatment urgently demand the development of novel antibiofilm …
recalcitrance to antibiotic treatment urgently demand the development of novel antibiofilm …
1, 3, 5-Triazines: A promising scaffold for anticancer drugs development
S Cascioferro, B Parrino, V Spanò, A Carbone… - European journal of …, 2017 - Elsevier
This review covering literature reports from the beginning of this century to 2016 describes
the synthetic pathways, the antitumor activity, the structure-activity relationship and …
the synthetic pathways, the antitumor activity, the structure-activity relationship and …
Scanning ion conductance microscopy reveals differences in the ionic environments of gram-positive and negative bacteria
K Cremin, BA Jones, J Teahan, GN Meloni… - Analytical …, 2020 - ACS Publications
This paper reports on the use of scanning ion conductance microscopy (SICM) to locally
map the ionic properties and charge environment of two live bacterial strains: the Gram …
map the ionic properties and charge environment of two live bacterial strains: the Gram …
Peptide-based strategies for overcoming biofilm-associated infections: A comprehensive review
T Manobala - Critical Reviews in Microbiology, 2024 - Taylor & Francis
Biofilms represent resilient microbial communities responsible for inducing chronic
infections in human subjects. Given the escalating challenges associated with antibiotic …
infections in human subjects. Given the escalating challenges associated with antibiotic …
Novel sulfonamide–triazine hybrid derivatives: docking, synthesis, and biological evaluation as anticancer agents
The biological benefits of trisubstituted 1, 3, 5-triazine derivatives include their ability to
reduce inflammation and fight cancer. A unique series of sulfonamide–triazine hybrid …
reduce inflammation and fight cancer. A unique series of sulfonamide–triazine hybrid …
Synthesis, characterizations, antitumor and antimicrobial evaluations of novel Mn (II) and Cu (II) complexes with NNN-tridentate s-triazine-Schiff base ligand
The new s-triazine hydrazone, 2, 4-bis (morpholin-4-yl)-6-[(E)-2-[1-(pyridin-2-yl) ethylidene]
hydrazin-1-yl]-1, 3, 5-triazine,(L) ligand was used to synthesize three new metal complexes …
hydrazin-1-yl]-1, 3, 5-triazine,(L) ligand was used to synthesize three new metal complexes …
AMPs as anti-biofilm agents for human therapy and prophylaxis
Microbial cells show a strong natural tendency to adhere to surfaces and to colonize them by
forming complex communities called biofilms. In this growth mode, biofilm-forming cells …
forming complex communities called biofilms. In this growth mode, biofilm-forming cells …
Treatment strategies targeting persister cell formation in bacterial pathogens
Persister cells are transiently antibiotic-tolerant and dormant subpopulations that are
produced to escape the effects of antibiotics within biofilms or planktonic cell populations …
produced to escape the effects of antibiotics within biofilms or planktonic cell populations …
Synthesis and evaluation of biological activities of tripodal imines and β-lactams attached to the 1, 3, 5-triazine nucleus
A novel collection of tripodal β-lactam derivatives with 1, 3, 5-triazine as the central core is
presented for the first time. The diastereoselective synthesis of tris-β-lactams was achieved …
presented for the first time. The diastereoselective synthesis of tris-β-lactams was achieved …