Old trade, new tricks: insights into the spontaneous mutation process from the partnering of classical mutation accumulation experiments with high-throughput …
Mutations spawn genetic variation which, in turn, fuels evolution. Hence, experimental
investigations into the rate and fitness effects of spontaneous mutations are central to the …
investigations into the rate and fitness effects of spontaneous mutations are central to the …
Bayesian inference of population size history from multiple loci
Background Effective population size (N e) is related to genetic variability and is a basic
parameter in many models of population genetics. A number of methods for inferring current …
parameter in many models of population genetics. A number of methods for inferring current …
Speciation through cytonuclear incompatibility: insights from yeast and implications for higher eukaryotes
JY Chou, JY Leu - Bioessays, 2010 - Wiley Online Library
Several features of the yeast mitochondrial genome, including high mutation rate, dynamic
genomic structure, small effective population size, and dispensability for cellular viability …
genomic structure, small effective population size, and dispensability for cellular viability …
An Incompatibility between a Mitochondrial tRNA and Its Nuclear-Encoded tRNA Synthetase Compromises Development and Fitness in Drosophila
Mitochondrial transcription, translation, and respiration require interactions between genes
encoded in two distinct genomes, generating the potential for mutations in nuclear and …
encoded in two distinct genomes, generating the potential for mutations in nuclear and …
New views on strand asymmetry in insect mitochondrial genomes
Strand asymmetry in nucleotide composition is a remarkable feature of animal mitochondrial
genomes. Understanding the mutation processes that shape strand asymmetry is essential …
genomes. Understanding the mutation processes that shape strand asymmetry is essential …
A mitochondria-specific mutational signature of aging: increased rate of A> G substitutions on the heavy strand
The mutational spectrum of the mitochondrial DNA (mtDNA) does not resemble any of the
known mutational signatures of the nuclear genome and variation in mtDNA mutational …
known mutational signatures of the nuclear genome and variation in mtDNA mutational …
Patterns of positive selection in seven ant genomes
The evolution of ants is marked by remarkable adaptations that allowed the development of
very complex social systems. To identify how ant-specific adaptations are associated with …
very complex social systems. To identify how ant-specific adaptations are associated with …
Expansion dating: calibrating molecular clocks in marine species from expansions onto the Sunda Shelf following the Last Glacial Maximum
The rate of change in DNA is an important parameter for understanding molecular evolution
and hence for inferences drawn from studies of phylogeography and phylogenetics. Most …
and hence for inferences drawn from studies of phylogeography and phylogenetics. Most …
Evolved genetic and phenotypic differences due to mitochondrial-nuclear interactions
The oxidative phosphorylation (OxPhos) pathway is responsible for most aerobic ATP
production and is the only pathway with both nuclear and mitochondrial encoded proteins …
production and is the only pathway with both nuclear and mitochondrial encoded proteins …
Pleiotropic Effects of a Mitochondrial–Nuclear Incompatibility Depend upon the Accelerating Effect of Temperature in Drosophila
Interactions between mitochondrial and nuclear gene products that underlie eukaryotic
energy metabolism can cause the fitness effects of mutations in one genome to be …
energy metabolism can cause the fitness effects of mutations in one genome to be …